published_or_final_version / Public Health / Master / Master of Public Health

Background Smoking is a well-established causal risk factor of premature death. The prevalence of smoking has been estimated to be more than 50% in Chinese men. However, previous reviews of the association between smoking and mortality from all-causes and lung cancer were mainly relied on developed countries. The current systematic review of cohort studies aims at summarizing the existing studies on the association of smoking with all-cause and lung cancer mortality in China. Methods Articles published from 1980 to 2014were searched systematically in databases including PubMed, EMBASE, China National Knowledge Infrastructure (CNKI) and Google scholar. Main results of all studies were extracted and summarized. Results A total of 14 cohort studies examining the association of smoking with all-cause and lung cancer mortality in Chinese populations were identified. Compared with never smoking, current smoking was associated with higher risks of all-cause and lung cancer mortality in all studies. The relative risks (RR) for current smokers were from 1.20 to 2.29 for all-cause mortality and from 2.44 to 9.40 for lung cancer mortality. Former smokers also showed higher RRs for all-cause mortality (RR=1.20-1.48) and for lung cancer mortality (RR=2.06-6.50) compared with never smokers. Furthermore, dose-response associations of increasing smoking categories with all-cause mortality and lung cancer mortality were observed in most of the studies. Conclusions The risk estimates for all-cause and lung cancer mortality from smoking in China were lower than those from the western countries suggesting that the tobacco epidemic is at an early stage in China. Further large cohort studies giving updated risk estimates are warranted for advocating stringent tobacco control policies in China. / published_or_final_version / Public Health / Master / Master of Public Health

published_or_final_version / Public Health / Master / Master of Public Health

Introduction: Due to the high prevalence of smoking in China, exposure to second hand smoke (SHS) is a serious public health issue. However, school-aged children’s behavioral responses to SHS exposure and the associated factors are unclear. Aims: This study aims to (a) identify the sources and settings of SHS exposure among school-aged sick children and their mothers in Guangzhou, China; (b) describe the behavioral responses of those children and mothers when exposed to SHS; and (c) examine the personal and environmental factors associated with children’s responses to SHS exposure. Methods: Qualitative and quantitative methods were combined in this study. Forty-five in-depth individual interviews were conducted to investigate sick school-aged children and their mothers’ understanding of and responses to SHS. A pilot survey was used to assess the validity and reliability of the questionnaire and the feasibility of the study. A cross-sectional survey was conducted with the children and their mothers at three hospitals in Guangzhou in 2012. All sick children who were aged 6 to 12 years, able to communicate in Mandarin Chinese, and not acutely or severely ill, along with their nonsmoking mothers, were invited to join this study. Results: A total of 339 pairs of sick children and their mothers were included in the data analysis. Of these pairs, 169 (49.9%) lived with smokers. All sick children and their mothers experienced high-level SHS and third hand smoke (THS) exposure inside or outside the home. Those living with nonsmokers were also at risk of household SHS and THS exposure from guests. Most of the sick school-aged children were unaware of the dangers of SHS and THS, while the mothers had a better understanding of SHS and THS. The majority of children would adopt self-protective behaviors when exposed to SHS. The regression model for children’s behavioral responses to SHS exposure by family smokers found two significant factors: amount of social support and family smoke-free policy. Five factors were associated with children’s behavioral responses to SHS exposure by guest smokers, including boys, living with smokers, amount of social support, family members informed of the dangers of smoking, and fathers protecting children from SHS. The amount of social support, and fathers protecting children from SHS were also associated with children’s behavioral responses to SHS exposure by stranger smokers. Conclusions: To our knowledge, this is the first study to describe self-protective behavioral responses to SHS exposure among sick school-aged children in mainland China and the personal and environmental factors associated with these responses. Boys, living with smokers, and a partial smoke-free policy at home were negatively related to children’s responses to SHS exposure; however, more information about smoking, fathers’ protection from SHS, and information about the harms of smoking by family members were associated with greater self-protection among sick school-aged children. Therefore, multiple-direction interventions should be considered for children’s health promotion about smoking and SHS. / published_or_final_version / Nursing Studies / Master / Master of Philosophy

published_or_final_version / Medical Sciences / Master / Master of Medical Sciences

published_or_final_version / Medical Sciences / Master / Master of Medical Sciences

published_or_final_version / Community Medicine / Doctoral / Doctor of Philosophy

published_or_final_version / Community Medicine / Doctoral / Doctor of Philosophy