The aim of the thesis is to design a steel structure of the parking building in the center of Brno. The plan dimensions of the building are 29 x 77.5 m including a missing corner of the dimensions 5 x 12.5 m in the southeast part of the construction. The construction of the parking building has 4 above-ground floors with the same layout and the fifth floor situated only in the middle section of the construction. Each floor is 3.5 m high. The total height of the construction in the place of the roofed part of the fifth floor is 17.5 m, otherwise 14 m. A spatial frame is the main load-bearing part consisting of 7 fields in the longitudinal direction and 5 fields in the transversal direction. The spatial frame is formed of columns and longitudinal and transversal girders. Steel-concrete composite joists are pin-supported among longitudinal girders. The construction of the parking building is solved in three versions considering different placing of columns to the base structure and different placing of longitudinal and transversal girders to the columns. The resulting draft is worked out in details. Roof cladding will be made using sandwich panels and walls will be made out of glass panels. The calculation has been done in Scia Engineer 2014 program and by manual calculation.