Effective aeromedical evacuation of casualties is one of the most important problems in military medical systems because high-priority casualties will not survive without timely medical care. The decision making process for aeromedical evacuation consists of the following components: (1) identifying which aeromedical evacuation asset (see figure 1) to dispatch to the casualty, (2) locating aeromedical evacuation assets strategically in anticipation of incoming demand, and (3) deciding which medical treatment facility to transport the casualty. These decisions are further complicated because prioritization of casualties is based on severity of injury while aeromedical evacuation assets and medical treatment facilities operate with varying capabilities. In this dissertation, discrete optimization models are developed to examine dispatch, delivery, and location logistics for the effective aeromedical evacuation of casualties in military medical systems.