Yes / A novel prestressed precast reinforced concrete (RC) beam-column joint, composed of prestressed tendons, stiffened steel sleeves, and high-strength bolts, having improved self-centring ability and assembly efficiency is proposed in this paper. Four prestressed precast RC joints assembled by steel sleeves and one cast-in-place RC joint were tested under cyclic loading to investigate the seismic response of the proposed joint. The main parameters studied are the axial compression ratio of columns, stirrup ratio in the core area of the proposed joint and effective prestress of tendons. The energy dissipation capacity, bearing capacity, and self-centring ability of the prestressed precast RC beam-column joints assembled by steel sleeves are higher than those measured for the cast-in-place RC joint. For the prestressed precast RC joints assembled by steel sleeves, both yield and ultimate displacements increase with the increase of the axial compression ratio, stirrup ratio and effective prestress, but the ductility decreases with the increase of the axial compression ratio and effective prestress. The increasing of axial compression ratio can lead to an increase in the energy dissipation capacity, shear capacity and residual displacement. Finally, formulae to predict the shear capacity of prestressed precast RC joint assembled by steel sleeves are proposed, being in good agreement with the experimental results. / The authors would like to thank the financial support provided by the Natural Science Foundation of Jiangsu Province, China (BK20201436), the Open Foundation of Jiangsu Province Engineering Research Center of Prefabricated Building and Intelligent Construction (2021), the Blue Project Youth Academic Leader of Colleges and Universities in Jiangsu Province (2020) and the Postgraduate Research & Practice Innovation Program of Jiangsu Province, China (KYCX21_3225).