The purpose of this study was to investigate the relationship between drug abuse and high school size. This thesis includes a survey which was conducted at Ball State University. The dependent variable was drug use; school size was the main independent variable and was positively related to drug use. Intervening variables were considered-parent/teacher relations, student/teacher interaction, participation in extracurricular activities, and peer acquaintanceship. Several control variables were also taken into consideration which were as follows: 1) size of city; 2) racial composition of high school; 3) per-capita income; 4) drug education programs; 5) religiosity of community; 6)educational aspirations; and finally 7) respondent's perceived class composition.Peer acquaintanceship had the opposite effect of what was originally hypothesized. Control variables which remained significant in the analyses were city size, income, and race. After including the significant control variables high school size was still significant at .05. According to these findings, future research on drug use and adolescents should take into consideration high school size. / Department of Sociology