Polymicrogyria (PMG) is one brain disease that mainly occurs in the pediatric brain. Heavy PMG will cause seizures, delayed development, and a series of problems. For this reason, it is critical to effectively identify PMG and start early treatment. Radiologists typically identify PMG through magnetic resonance imaging scans. In this study, we create and open a pediatric MRI dataset (named PPMR dataset) including PMG and controls from the Children's Hospital of Eastern Ontario (CHEO), Ottawa, Canada. The difference between PMG MRIs and control MRIs is subtle and the true distribution of the features of the disease is unknown. Hence, we propose a novel center-based deep contrastive metric learning loss function (named cDCM Loss) to deal with this difficult problem. Cross-entropy-based loss functions do not lead to models with good generalization on small and imbalanced dataset with partially known distributions. We conduct exhaustive experiments on a modified CIFAR-10 dataset to demonstrate the efficacy of our proposed loss function compared to cross-entropy-based loss functions and the state-of-the-art Deep SAD loss function. Additionally, based on our proposed loss function, we customize a deep learning model structure that integrates dilated convolution, squeeze-and-excitation blocks and feature fusion for our PPMR dataset, to achieve 92.01% recall. Since our suggested method is a computer-aided tool to assist radiologists in selecting potential PMG MRIs, 55.04% precision is acceptable. To our best knowledge, this research is the first to apply machine learning techniques to identify PMG only from MRI and our innovative method achieves better results than baseline methods.

This work addresses the following research question: Can we detect videogame glitches using Convolutional Neural Networks? Focusing on the most common types of glitches, texture glitches (Stretched, Lower Resolution, Missing, and Placeholder). We first systematically generate a dataset with both images with texture glitches and normal samples.  To detect the faulty images we try both Classification and Semantic Segmentation approaches, with a clear focus on the former. The best setting in classification uses a ShuffleNetV2 architecture and obtains precisions of 80.0%, 64.3%, 99.2%, and 97.0% in the respective glitch classes Stretched, Lower Resolution, Missing, and Placeholder. All of this with a low false positive rate of 6.7%. To complement this study, we also discuss how the models extrapolate to different graphical environments, which are the main sources of confusion for the model, how to estimate the confidence of the network, and ways to interpret the internal behavior of the models. / Detta projekt svarar på följande forskningsfråga: Kan man använda Convolutional Neural Networks för att upptäcka felaktiga bilder i videospel? Vi fokuserar på de vanligast förekommande grafiska defekter i videospel, felaktiga textures (sträckt, lågupplöst, saknas och platshållare). Med hjälp av en systematisk process genererar vi data med både normala och felaktiga bilder. För att hitta defekter använder vi CNN via både Classification och Semantic Segmentation, med fokus på den första metoden. Den bäst presterande Classification-modellen baseras på ShuffleNetV2 och når 80.0%, 64.3%, 99.2% och 97.0% precision på respektive sträckt-, lågupplöst-, saknas- och platshållare-buggar. Detta medan endast 6.7% av negativa datapunkter felaktigt klassifieras som positiva. Denna undersökning ser även till hur modellen generaliserar till olika grafiska miljöer, vilka de primära orsakerna till förvirring hos modellen är, hur man kan bedöma säkerheten i nätverkets prediktion och hur man bättre kan förstå modellens interna struktur.