This research paper investigated the performance of the supply chain system in the pharmaceutical industry in Pakistan. The study was based on the hypothesis that the adopted supply chain systems lack proper structures to deal with the challenges of the business environment in which they operate, and as such were underperforming. Therefore, the objective was to ascertain the nature and the dynamics of the SCM (Supply Chain Management) system used in the drug industry. The objectives of the research were anchored on three factors that include Supply Chain Flexibility/Agility Performance, Supply Chain Resource Performance, and Supply Chain Output Performance. These three metrics were used to describe the independent variable which comprises the supply chain performance of Pakistan’s pharmaceutical industry. The research data was collected through questionnaires that would make it possible to analyze and interpret information gathered. The questions were administered to a sample of the players that represent every sector of the industry (multinationals, local manufacturers, retailers, and regulators). The final results of the study support or discourage the hypotheses that 1) Manufacturers struggle to manage lead-time as a result of factors such as government. 2) Manufacturers lack satisfactory levels of performance in terms of Supply Chain Flexibility/Agility Performance, Supply Chain Resource Performance, and Supply Chain Output Performance.