Supply chains have become more complex in the global economy, which has made supply chain disruptions inevitable. Disruptions can cause loss of profitability and hinder business growth. The goal of this multiple case study was to explore strategies to mitigate the effects of disruption in grocery store supply chains. The conceptual framework for this study was the resource dependency theory, which stipulates that firms rely on other businesses in the external environment for critical resources to create a competitive edge. Four purposively selected participants from 4 grocery store businesses in Northwest Arkansas participated in semistructured interviews and provided organizational documentation for this study. The participants were supply chain managers who had knowledge about disruptions and had successfully mitigated disruptions in their grocery stores' supply chains. Yin's 5-step process was used to analyze data, which involved compiling the database, disassembling data, reassembling data, interpreting data, and making a conclusion. Four themes emerged from the data analysis: supply chain partners' collaboration, multiple supply base and supplier qualification, inventory management, and information technology and communication. The uninterrupted flow of grocery merchandise to the community could result in a positive social change by helping to ensure that community members have timely access to food.