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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.

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Directed differentiation of mouse embryonic stem cells into neocortical output neurons

Sadegh, Cameron 10 October 2015 (has links)
During development of the neocortex, many diverse projection neuron subtypes are generated under regulation of cell-extrinsic and cell-intrinsic controls. One broad projection neuron class, corticofugal projection neurons (CFuPN), is the primary output neuron population of the neocortex. CFuPN axons innervate sub-cortical targets including thalamus, striatum, brainstem, and spinal cord.
Neurosciences
Developmental biology
Biomedical engineering
Corticofugal projection neurons
Corticospinal motor neurons
Directed Differentiation
Embryonic stem cells
Neocortex
Synthetic modified RNA

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