As Total Building Commissioning (TBCX) gaining acceptance and becoming a required process for federal, state and LEED projects, the required system guidelines are likewise being developed per Guideline 0-2005 recommendations. One of the most essential systems of any construction process is the structural system; however, there has been limited research in developing a guideline dedicated to structural systems. The Owner's Project Requirement (OPR) is the heart and soul of every guideline, in which Owners specify the requirements of the project in each system. A well-developed OPR for any system will guide the project stakeholders to achieve this goal; it will also, identify the responsibility of professionals in each system of the TBCX. To address this need, this fundamental research will develop a framework for the Owner's Project Requirement (OPR) for Total Structural Systems (OPRTSS). The goal of this research is to develop a model for identifying and implementing the major design and construction variables that impact structural performance of a project, especially during project delivery of concrete or steel framed projects; these are variables that are generally not defined or required by contracts, applicable building codes or engineering principles; that need to be outlined at the pre-design stage. Then, these variables are incorporated into the OPR to reduce the design and construction process uncertainty and help to achieve Owner's requirements for the project. Consequently this will increase Owners satisfaction, quality of the built environment and reduce time, cost and litigation.