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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.

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A Comparison of Microarray Analyses: A Mixed Models Approach Versus the Significance Analysis of Microarrays

Stephens, Nathan Wallace 20 November 2006 (has links) (PDF)
DNA microarrays are a relatively new technology for assessing the expression levels of thousands of genes simultaneously. Researchers hope to find genes that are differentially expressed by hybridizing cDNA from known treatment sources with various genes spotted on the microarrays. The large number of tests involved in analyzing microarrays has raised new questions in multiple testing. Several approaches for identifying differentially expressed genes have been proposed. This paper considers two: (1) a mixed models approach, and (2) the Signiffcance Analysis of Microarrays.
Microarray
Significance Analysis of Microarrays
Mixed Models
Multiple Testing
Statistics
Bioconductor
Resampling
Normalization
Miss Rate
Tail Strength
False Discovery Rate
FDR
pFDR
BYU
SAS
SAMR
SAM
SMA
LPS
KNNImpute
FWER
Statistics and Probability

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