Constructing a road is a complex process that may be represented as a series of correlated steps, from the planning to the construction and usage of the new road. At the heart of this process, the preliminary and detailed design stages are key elements that will ensure the quality and the adequacy of the final solution regarding the constraints and objectives of the project. In particular, infrastructure layout and design will have a strong impact on the global performances of the road in operational conditions. Among them, road safety, mobility, environment preservation, noise pollution limitation, economic feasibility and viability of the project, or even its socio-economic impact at the local level. Consequently, it is crucial to offer engineers and road planners some tools and methods that may assist them in designing and selecting the most efficient solutions considering the distinctive features of each design problem. In this work, a multicriteria analysis methodology is developed to carry out an integrated and preventive assessment of road projects at the design stage by considering both their safety performances and some economic and environmental aspects. Its purpose is to support design engineers in the analysis of their projects and the identification of innovative, consistent and effective solutions. The proposed methodology is composed of two main research frameworks. On the one hand, the road design problem is addressed by focusing successively on the structuring of the multicriteria problem, the identification of the approximate set of non-dominated solutions using a genetic algorithm (based on NSGA-II), and the application of the methodology to a real road design project. On the other hand, the methodological development of a multicriteria interval clustering model was performed (based on PROMETHEE). Due to the applicability of this model to the studied problem, the interactions between the two frameworks are also analysed. / Doctorat en Sciences de l'ingénieur et technologie / The present PhD thesis is an aggregation of published contributions related to the application of multicriteria analysis to the evaluation of road projects at the design stage. The aim of the two introductory chapters is to offer a synthesised and critical presentation of the scientific contributions that constitute the PhD thesis. The complete version of the journal articles and preprints are found in Chapters 3 to 6. In the appendices, we also provide reprints of conference papers that are usually related to one of the main contributions of the thesis. / info:eu-repo/semantics/nonPublished