Abstract Most enterprises reinforce themselves with the Management Information System and the intranet to get information promptly and also the internet to enhance the relationships with customers as one of the most important strategies to survive in the competitive environment. The key success factors of Management Information System are mature system planning, friendly design for users, and end user¡¦s participation, which is recognized as the most crucial factor of the above. Therefore, how to evaluate end user¡¦s satisfaction and acceptance on the Management Information System becomes the most interesting topic for the managers. This study explores the technology acceptance of the end users of Shop Information System from the model of TAM2 (Technology Acceptance Model II). And its purpose is to find the influent factors of Intention to Use and Use Behavior of the end users of Shop Information System. The managers can carry out or improve the MIS according to this study. After the research, this study indicates that there are four components that influenced the degree of acceptance of technology, included the Usefulness of system, the result demonstrability; the ease of use, and ought to use or not. Different factors under several conditions in demography significantly influence the intention of users. The managers can improve the management information system according to the finding of this study.