Text in English / Previous studies have reported a high prevalence of HIV and AIDS among adolescent girls. It is estimated that there are 5,24 million people living with HIV/AIDS (PLWHA). These estimates would mean that about 2.36 million people living with HIV/AIDS would be young women and girls aged 15-24 years. The latest household survey conducted by the Human Science Research Council (HSRC) revealed that the prevalence of HIV is three to seven fold in girls and young women aged 15-24 than boys and young men (HSRC 2014) This resurgence in HIV incidence is occurring at a time when it is believed the epidemic has reached a plateau following aggressive behavioural, biomedical and structural interventions by the Department of Health, Non-Governmental Organizations (NGO) and civil society in general. A probability sampling method, involving a random selection of elements was used to select 130 young women and girls aged 18-24 presenting at Dr George Mukhari Academic Hospital by simple random sampling. Data were collected by self-administering questionnaires. High unemployment and greater age-disparity in the relationships were found to have a direct correlation with HIV incidence in the population under study. This study also shows that inconsistent condom use, low rate of medical male circumcision of male partners, coupled with lower HIV counselling and testing than the national average, was associated with new HIV infections, in spite of high level of condom availability, knowledge of HIV issues and an exposure to an array of behavioural change communication interventions. / Health Studies / M.A. (Public Health)