This thesis studies the possibility of using the Monte Carlo simulation program FLUKA to determine the neutron induced radioactivity of concrete walls at the The Svedberg Laboratory (TSL) in Uppsala. If a simulation of the activation would produce reliable results, it would be a useful complement to measurements for the decommissioning and clearance of the buildings of the facility. An experiment was performed in which a concrete core was taken from one of the non-activated walls in the facility. The core was cut into samples and irradiated with a neutron beam. The samples were then measured in a gamma-ray spectroscopy setup, by which the produced radioactive nuclides were identified and their activities determined. The same setup was then simulated in FLUKA. A comparison of the simulations and the measurements shows that the average activity for all nuclides obtained with FLUKA is similar to the measured one, however with large differences for some nuclides. The average ratio of the simulated and measured activities or all nuclides is 1.07 with a standard deviation of 0.55. The obtained results may be useful for future radiological clearance work at TSL.