Thesis (doctoral)--Rijksuniversiteit te Groningen.

Thesis (doctoral)--Københavns universitet.

Thesis (Ph. D.)--University of Chicago, 1941. / Reproduced from type-written copy. "Literature cited": p. 15.

Thesis (Ph. D.)--University of Chicago, 1921. / "Private edition, distributed by the University of Chicago Libraries, Chicago, Illinois." "Reprinted from the Journal of biological chemistry, vol. XLV, no. 2, 1921; vol. LIV, no. 1, 1922; the American journal of physiology, vol. LVI, no. 1, 1921." Bibliography: p. 181, 18.

Inaug.-diss.-Bern. / "Literaturverzeichnis": p. [33]-36.

Thesis (Ph. D.)--Ohio State University, 2007. / Title from first page of PDF file. Includes bibliographical references (p. 117-135).

Thesis (PH. D.)--University of Chicago, 1921. / "Private edition, distributed by the University of Chicago Libraries, Chicago, Illinois." "Reprinted from the Journal of biological chemistry, vol. XLV, no. 2, 1921; vol. LIV, no. 1, 1922; the American journal of physiology, vol. LVI, no. 1, 1921." Bibliography: p. 181, 18. Also available on the Internet.

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Hyperplasia was induced by physical and chemical means. The resulting goitres were examined by electron microscopy, and the basement membranes were analyzed by stereological methods. The basement membrane in experimental colloid goitre was found to be significantly thinner than its control. A consideration of the course of the various goitres and of the chemical nature of basement membranes leads to the conclusion that the thinning of the basement membrane was the result of stretching. / Science, Faculty of / Zoology, Department of / Graduate

Three approaches were made to study the interrelations between thyroid function and vitamin A in avian metabolism. These were a histological assessment of the activity of the thyroid gland as it is affected by hypervitaminosis A, the effect of hypervitaminosis A on the incubation time of eggs injected with different levels of vitamin A alcohol and palmitate, and finally the effects of hypervitaminosis A on thyroidal uptake and release of radioiodine by chickens. These studies yielded the following observations. CI) Histological -measurements indicated that dietary hypervitaminosis A can depress the secretion of thyroid stimulating hormone. (2) The effect of hypervitaminosis A on thyroid activity as affected by environmental temperature. (3) Vitamin A palmitate and alcohol prolong incubation time. The alcohol form has, in addition, an adverse effect on embryonic development which is manifested in hemorrhaging and malformation of the embryo. (4) Vitamin A in excess may either depress or stimulate thyroidal uptake of radioiodine depending upon an unidentified component of the environment. (5) Vitamin A in excess affects the endocrine system. This is indicated by an increase in size of the thyroid and adrenal glands and a decrease in size of combs and testes. / Land and Food Systems, Faculty of / Graduate