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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Aprendizado espacial-temporal em um ambiente complexo sem restri??o alimentar em ratos

Oliveira, Alexsandro Lamarck Duarte 20 September 2007 (has links)
Made available in DSpace on 2014-12-17T15:36:50Z (GMT). No. of bitstreams: 1 AlexsandroLDO.pdf: 329212 bytes, checksum: 72e9f94d5f2af1bff3f6180d3b9b5aa7 (MD5) Previous issue date: 2007-09-20 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior / Timeplace learning is the capacity of organisms to associate both space and time with a biological relevant stimulus such as food. Experiments are usually done with food restricted animals due to the belief that food system activation is necessary for timeplace learning. Another line of thought suggest that, in addition to food system activation, response cost should be increased to effectively allow timeplace discrimination. The purpose of this experiment was to test whether a complex environment, which presumably implied in a heightened response cost, would facilitate timeplace association in satiated rats using a highly palatable food as reward. Nine rats were trained in a timeplace task for 30 nonconsecutive days. A large experimental box (1x1m) divided in four compartments was used. To access each compartment the animal had to overcome a series of obstacles such as ramps, staircases and mazes. Two feeders localized in opposite compartments were rewarded with sunflower seeds in two daily sessions. One feeder offered the reward during the morning sessions while the second feeder in afternoon sessions. After the 15th day of training, the animals began to show a preference for the correct feeder during the correct time of day expressed by increased frequency of visits as well as lower latency to access the feeders. These results suggest that satiated animals are also capable of learning a timespace task as far as the experimental context is complex enough to result in a higher response cost / O aprendizado espacialtemporal ? a capacidade dos organismos em associar espa?o e tempo com um est?mulo biologicamente relevante, tal como a comida. Experimentos geralmente s?o feitos com animais em restri??o alimentar, devido acreditarse que a ativa??o do sistema alimentar ? necess?ria para a mem?ria espacialtemporal. Outra linha de pensamento sugere que, em conjunto com a ativa??o do sistema alimentar, o custo de resposta deve ser aumentado para efetivamente permitirse a discrimina??o espa?otempo. O prop?sito desta experi?ncia foi testar se um ambiente complexo, presumivelmente implicando num aumento do custo de resposta, poderia facilitar a associa??o espa?otempo em animais saciados, utilizando um alimento altamente palat?vel como recompensa. Nove ratos foram treinados em uma tarefa espacialtemporal por 30 dias n?oconsecutivos. Uma caixa experimental grande (1m x 1m x 0,5m) dividida em quatro compartimentos foi utilizada. Para acessar cada compartimento o animal tinha que vencer uma s?rie de obst?culos, tais como rampas, escadas e labirintos. Dois comedouros localizados em compartimentos opostos forneciam sementes de girassol como recompensa em duas sess?es di?rias. Um comedouro ofereceu recompensa durante as sess?es matutinas enquanto o segundo comedouro ofereceu recompensa durante as sess?es vespertinas. Depois do 15? dia de treino, os animais come?aram a demonstrar uma prefer?ncia pelo comedouro correto na hora correta do dia, expressa tanto pelo aumento na freq??ncia de visitas quanto na diminui??o da lat?ncia para acessar o comedouro correto. Estes resultados sugerem que animais saciados tamb?m s?o capazes de aprender uma tarefa espacialtemporal, desde que o contexto experimental seja complexo o bastante para resultar num custo de resposta mais alto

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