• Refine Query
  • Source
  • Publication year
  • to
  • Language
  • 75
  • 17
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 1
  • 1
  • 1
  • Tagged with
  • 127
  • 127
  • 37
  • 31
  • 26
  • 22
  • 17
  • 15
  • 15
  • 14
  • 12
  • 12
  • 12
  • 12
  • 10
  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.

The development of targeted TiO2 nanoparticles for the detection of trastuzumab responsive breast tumours by positron emission tomography

Cheyne, Richard William January 2011 (has links)
Screening of breast cancer patients for their tumour's prognostic marker status is necessary in determining the most suitable course of treatment. This is particularly important in the assessment of HER-2 expression status in identifying candidates who may respond to trastuzumab therapy. Current methods are limited in their effectiveness in accurately determining actual marker status.Discussed herein is an investigation into the development of a titanium dioxide nanoparticle system which may be applied as a medical imaging methodology through the use of positron emission tomography to gauge accurately a patient's HER-2 expression status in identifying candidates for trastuzumab therapy. The initial synthesis of organically coated ultra-small titanium dioxide nanoparticles is discussed in depth with respect to a range of coating molecules and further functionalisation. Additionally, methodology to elicit an exchange of these coat molecules is explored in detail resulting in the generation of TiO2 nanoparticles capable of forming long-term stable suspensions in water. An exploration of the synthesis of fluoride accepting groups for use in generating radiolabelled compounds is explored both successfully and unsuccessfully leading to the development of conditions suitable for radiolabelling aryltrifluoroborate compounds. Attempts to then combine these radionuclide accepting groups with biologically compatible TiO2 nanoparticles are discussed as an initial step toward the generation of a potential PET tracer. However, while this conjugation was achieved, a successful demonstration of the radiolabelling was not achieved requiring further focus on modulating the nanoparticle to easily allow its recovery from such reactions. Finally, an investigation into the effects of trastuzumab and cetuximab on FDG uptake by cells in vitro is discussed with respect to the potential of monitoring disease response to these drugs with conventional FDG-PET.

Spatio-temporal image reconstructiuon for positron emission tomography

Cockbill, Andrew John Paul January 2011 (has links)
No description available.

Quantification challenges in simultaneous PET and MR

Herrick, Peter David Edmund January 2013 (has links)
No description available.

Positron emission tomography in the management of neuroendocrine tumors /

Örlefors, Håkan, January 2003 (has links)
Diss. (sammanfattning) Uppsala : Univ., 2003. / Härtill 5 uppsatser.

Quantitative imaging with PET : performance and applications of ⁷⁶Br, ⁵²Fe, ¹¹⁰mIn and ¹³⁴La /

Lubberink, Mark, January 1900 (has links)
Diss. (sammanfattning) Uppsala : Univ., 2001. / Härtill 6 uppsatser.

Development of a new silicon based detector module for PET

Hooper, Peter R. January 2003 (has links)
Thesis (M.Sc.(HONS))--University of Wollongong, 2003. / Typescript. Bibliographical references: leaf 83-89.

System identification in dynamic positron emission tomography /

Deng, Chuang. January 2008 (has links)
Thesis (M.Phil.)--Hong Kong University of Science and Technology, 2008. / Includes bibliographical references (leaves 52-59). Also available in electronic version.

Investigation of distance-dependent blurring in spect /

Xu, Beilei. January 1999 (has links)
Thesis (Ph. D.)--University of Chicago, August 1999. / Includes bibliographical references. Also available on the Internet.

Multi camera stereo and tracking patient motion for SPECT scanning systems

Nadella, Suman. January 2005 (has links)
Thesis (M.S.)--Worcester Polytechnic Institute. / Keywords: Feature matching in multiple cameras; Multi camera stereo computation; Patient Motion Tracking; SPECT Imaging Includes bibliographical references. (p.84-88)

A Quad BGO Detector for High Resolution Positron Tomography

Roney, J. Michael 01 1900 (has links)
No description available.

Page generated in 0.0921 seconds