abstract: The past decades have seen a significant shift in the expectations and requirements re-lated to power system analysis tools. Investigations into major power grid disturbances have suggested the need for more comprehensive assessment methods. Accordingly, sig-nificant research in recent years has focused on the development of better power system models and efficient techniques for analyzing power system operability. The work done in this report focusses on two such topics 1. Analysis of load model parameter uncertainty and sensitivity based pa-rameter estimation for power system studies 2. A systematic approach to n-1-1 analysis for power system security as-sessment To assess the effect of load model parameter uncertainty, a trajectory sensitivity based approach is proposed in this work. Trajectory sensitivity analysis provides a sys-tematic approach to study the impact of parameter uncertainty on power system re-sponse to disturbances. Furthermore, the non-smooth nature of the composite load model presents some additional challenges to sensitivity analysis in a realistic power system. Accordingly, the impact of the non-smooth nature of load models on the sensitivity analysis is addressed in this work. The study was performed using the Western Electrici-ty Coordinating Council (WECC) system model. To address the issue of load model pa-rameter estimation, a sensitivity based load model parameter estimation technique is presented in this work. A detailed discussion on utilizing sensitivities to improve the ac-curacy and efficiency of the parameter estimation process is also presented in this work. Cascading outages can have a catastrophic impact on power systems. As such, the NERC transmission planning (TPL) standards requires utilities to plan for n¬-1-1 out-ages. However, such analyses can be computationally burdensome for any realistic pow-er system owing to the staggering number of possible n-1-1 contingencies. To address this problem, the report proposes a systematic approach to analyze n-1-1 contingencies in a computationally tractable manner for power system security assessment. The pro-posed approach addresses both static and dynamic security assessment. The proposed methods have been tested on the WECC system. / Dissertation/Thesis / Doctoral Dissertation Electrical Engineering 2016