abstract: Music therapy literature provides evidence that the use of music is very effective in improving daily living skills for people with Autism Spectrum Disorder (ASD) all over the world. However, each country may have and use their preferred music therapy approaches and interventions for clients with ASD because of cultural differences although music therapy comes from the same origin. The aim of this research was to discover the cultural differences between American and Korean parents of children with ASD by comparing two countries in various categories, such as care systems, benefits and challenges in raising children with ASD, and therapeutic approaches in music therapy and other therapies used for these children. The data that was gathered from the survey consisted of 4 participant groups: American parents, Korean parents, American music therapists, and Korean music therapists. This study examined the differences and similarities in the parental perspectives of children with ASD and music therapy treatment practices for individuals with ASD between two countries through the survey methods, integrating quantitative (closed-ended) and qualitative (open-ended) survey questions. The results of the findings indicated that there were several kinds of cultural differences in treating children with ASD, such as care systems, benefits and challenges in raising their children, and therapies used for children with ASD between American and Korean children. Overall, Korean parent participants reported experiencing fewer benefits than American parent participants in the question concerning country-level benefits. Statistically speaking, the study could not find any significant differences in using therapies for children with ASD as well as music therapy treatment practices between America and Korea. However, the study found that there were some differences in the music therapy approaches and preferred music therapy interventions for ASD-diagnosed children which were summarized in responses from parents and therapists. The primary difference noticed that American music therapists preferred behavioral and neurologic techniques, while Korean music therapists preferred behavioral and Nordoff-Robbins techniques. Because of some of the study limitations, the results may not be generalizable. In future research, many more participants need to be engaged with a narrow range of conditions. / Dissertation/Thesis / Masters Thesis Music Therapy 2016

Bovine trypanosomosis is a serious constraint to livestock development in large parts of Mozambique. In most areas where tsetse flies are present, the disease in livestock is controlled using curative and prophylactic trypanocidal drugs. Those drugs have been used for many years and new drugs are unlikely to become available in the near future. As a result, trypanosomes have developed resistance against the currently available trypanocidal compounds. Drug resistance has been detected in various African countries and is a serious impediment to the control of livestock trypanosomosis. A study was initiated to determine whether drug resistant trypanosome strains are present in Zambézia Province of Mozambique. The aim of this study was to determine the sensitivity of Trypanosoma congolense isolates from Chinde, Nicoadala and Maganja da Costa Districts to diminazene aceturate, isometamidium chloride and homidium chloride. To assess the effect of the farming system and the intensity of drug regimens on the development of drug resistance, trypanosome isolates were collected from cattle from subsistence, semisubsistence and commercial livestock production systems. Drug-use practices in each of the production systems were determined using a questionnaire. The methodology used to assess the level of drugs resistance in the trypanosome isolates was the standardized method described by Eisler et al. (2001). Seven isolates were selected for resistance testing. For each of the seven isolates, five different doses varying between 0.01-20 mg/kg body weight for isometamidium chloride, 0.01-10 mg/kg body weight for homidium chloride and 1-30 mg/kg body weight for diminazene aceturate were used. For each dose rate six mice were treated intraperitoneally with the appropriate quantity of the drug dissolved in 0.2 ml of sterile distilled water 24 hours after the inoculation of the blood containing the trypanosomes. The control mice (six mice per trypanocidal drug) received the same amount of water without the drug. In four of the seven isolates high levels of multiple drug resistance (diminazene aceturate and isometamidium chloride) were detected. One isolate had a low level of multiple (diminazene aceturate and isometamidium chloride) drug resistance. Two isolates were susceptible to both diminazene aceturate and isometamidium chloride. One of those was highly susceptible to isometamidium chloride even at the lowest dose rate. The observed levels of drug resistance could in most cases be correlated to the drug-use practices in the particular livestock production system. The results obtained from homidium chloride treatment are not conclusive, because most the mice cured after receiving 10 mg/kg body weight of the drug. Hence more research is required to establish the homidium threshold in mice. The results of this study should be useful to define the strategy of disease control in places where resistance of trypanocide were been reported. / Dissertation (MSc (Veterinary Science))--University of Pretoria, 2005. / Veterinary Tropical Diseases / unrestricted