Thesis (M.S.H.S.A.)--Regis University, Denver, Colo., 2008. / Title from PDF title page (viewed on May 27, 2009). Includes bibliographical references.

BACKGROUND: Quality of life is defined by WHO as an individual perception of one's own position in life, taking into account cultural aspects of the society and a system of values in which the individual lives, as well as his/her goals, standard of living and interests. Because quality of life measure is strongly a subjective measure, it can only be assessed by the individual himself/herself. AIMS: The aim of this thesis was to compare of the quality of life of drug users before and after institutional treatment. SAMPLE AND METHODS: WHOQOL- BREF questionnaire was employed to collect the data. A research sample consisted of all clients (both men and women) in the institutional treatment at the department of treatment of dependencies at the Clinic of Addictology, The clients filled the questionnaire in before treatment entry or within the first week after treatment entry, and at the release from the treatment. RESULTS: None of the clients was very satisfied with his/her quality of life before treatment. After treatment, the quality of life was perceived as positive rather by women. After treatment, 44% of women found their quality of life good, whereas it was assessed as very good by 13% of women. The overall perception of the quality of life in the male population has not changed much. Regarding the...

Tyrimo tikslas - išanalizuoti priešinės liaukos vėžiu sergančių pacientų, 2007–2010 metais gydytų brachiterapija, radioaktyviojo Jodo-125 šaltinių implantavimo kokybę ir nepageidaujamą poveikį. Įvade išdėstomi tyrimo tikslai bei uždaviniai, pateikiama literatūros apžvalga, kurioje apibendrinamos pagrindinės su nagrinėjama tema susijusios problemos. Atskirame skyriuje aprašyta tyrimo metodika. Disertacijoje išnagrinėta laisvų ir skirtingais atstumais į grandinėlę sujungtų Jodo-125 šaltinių implantavimo kokybės skirtumais gydant priešinės liaukos vėžį bei dozimetrijos po implantacijos atlikimo laiko įtaką implantacijos rezultatų vertinimui. Atskirai analizuotas nepageidaujamas gydymo poveikis. Įvertinti su priešinės liaukos vėžio gydymu Jodo-125 šaltiniais susiję šlapinimosi sutrikimai, išanalizuoti erekcijos sutrikimai ir juos sukeliančtys veiksniai po Jodo-125 šaltinių implantavimo, nustatytos kraujavimo iš tiesiosios žarnos dažnio sąsajos su klinikiniais ir dozimetriniais parametrais. / Aim of this study - to analyze implant quality and treatment toxicity in prostate cancer patients, treated with Iodine-125 seeds brachytherapy during the perios of 2007 – 2010 years. Initial dissertation chapters covers study aims and objectives. Literature data about prostate brachytherapy with Iodine-125 seeds are analysed. Material and methods are thorougly described. Data about implant quality differences in prostate cancer patients, treated with loose and linked seeds, are presented. Influence of postimplant dosimetry time to evaluation of Iodine-125 implantation results is analysed. Another part of this work is dedicated to toxicity of Iodine-125 seeds brachytherapy. Various aspects of treatment side effects are evaluated urinary disorders and erectile dysfunction. Association of risk of rectal bleeding after Iodine–125 brachytherapy with clinical and dosimetry parameters is assesed.

Made available in DSpace on 2014-12-17T14:13:53Z (GMT). No. of bitstreams: 1 AnaEOM_TESE.pdf: 1417681 bytes, checksum: d2404c92b829058e4bb3bf9215331009 (MD5) Previous issue date: 2014-07-21 / This study was developed with the aim of analyzing the effectiveness of renal transplantation on quality of life of kidney recipients in the Rio Grande do Norte State. This is a descriptive study with longitudinal design, panel type with quantitative approach to data analysis. The Quality of Life (QoL) of chronic disease kidney patients before and after kidney transplantation was assessed by the WHOQOL-bref, The population consisted of patients in pre and post-renal transplantation, the sample had 63 patients older than 18 years. The study was conducted after approval by the Research Ethics Committee of the Onofre Lopes University Hospital, Federal University of Rio Grande do Norte, No. CAAE 0008.0.294.000-10. Data collection was performed at a referral center for renal transplantation in Rio Grande do Norte, from May 2010 to May 2013. Data were analyzed using descriptive statistics and presented in tables and graphs. For statistical analyzes, Microsoft Excel XP and SPSS 15.0 software were used. The tests used were simple variance (ANOVA), t-test, Mann-Whitney and Wilcoxon test to compare means, and Spearman correlations. P values <0.05 were considered significant. The demographic data showed a predominance of people between 18 and 45 years (68.2%) with a mean age of 39.9 years (SD 12.2), male (63.5%), married (58.7%), with children (51.0%). Regarding the education level was observed that 49.2% of participants had completed primary school, and most did not engage in any work activity (90.4%) during the study period. Hemodialysis was the predominant renal replacement therapy (96.8%) and the average waiting time for execution of transplantation was 1.9 years (SD 1.9). Comparison of QoL before and after transplantation showed significant differences in all areas analyzed, demonstrating that kidney transplantation had a positive impact on QoL in chronic renal patients undergoing kidney transplantation. Sociodemographic factors did not influence the quality of life in this group of patients, indicating that transplantation was the main factor to explain the improvement in quality of life. Thus, the alternative hypothesis of the study was accept, that there is a significant difference in quality of life before and after kidney transplant. It is expected that the results of this study may contribute to the development of strategies to encourage organ donation and kidney transplantation process / Este estudo foi desenvolvido com o objetivo de analisar a efetividade do transplante renal na qualidade de vida dos receptores no Estado do Rio Grande do Norte. Trata-se de um estudo descritivo, com delineamento longitudinal do tipo painel, com abordagem quantitativa de tratamento e an?lise dos dados. Para a avalia??o da Qualidade de Vida (QV) dos pacientes renais cr?nicos antes e ap?s o transplante de rim utilizou-se o WHOQOL-bref. A pesquisa foi desenvolvida ap?s aprova??o do Comit? de ?tica e Pesquisa do Hospital Universit?rio Onofre Lopes da Universidade Federal do Rio Grande do Norte, CAAE n? 0008.0.294.000-10. A popula??o constou de pacientes em acompanhamento ambulatorial pr? e p?s-transplante renal, sendo a amostra composta por 63 pacientes maiores de 18 anos. A coleta de dados foi realizada no centro de refer?ncia para transplante renal no Rio Grande do Norte, de maio de 2010 a maio de 2013. Os dados foram analisados por meio da estat?stica descritiva e apresentados em forma de tabelas e gr?ficos. Para as an?lises estat?sticas foram utilizados os programas Microsoft-Excel XP e SPSS 15.0. Os testes utilizados foram vari?ncia simples (ANOVA), teste t, Mann-Whitney e Wilcoxon, para compara??o de m?dias, al?m de Correla??es de Spearman. Valores de p<0,05 foram considerados significativos. Os dados sociodemogr?ficos mostraram predom?nio de pessoas entre 18 e 45 anos (68,2%), com idade m?dia de 39,9 anos (DP 12,2), do sexo masculino (63,5%), casados (58,7%) e com filhos (51,0%). Quanto ao n?vel de escolaridade observou-se que 49,2% dos participantes tinham ensino fundamental completo e a maior parte n?o desenvolvia nenhuma atividade laboral (90,4%) no per?odo do estudo. A hemodi?lise foi a terapia renal substitutiva predominante (96,8%) e o tempo m?dio de espera pela efetiva??o do transplante foi de 1,9 anos (DP 1,9). A compara??o da QV antes e ap?s o transplante mostrou diferen?a significativa em todos os dom?nios analisados, demonstrando que o transplante renal teve impacto positivo na QV de pacientes renais cr?nicos submetidos a transplante renal. Os fatores sociodemogr?ficos n?o influenciaram a qualidade de vida neste grupo de pacientes, indicando que o transplante foi o principal fator para explicar a melhora na qualidade de vida. Assim, se aceita a hip?tese alternativa do estudo, de que h? diferen?a significativa na qualidade de vida de receptores de rim antes e ap?s o transplante. Espera-se que os resultados desse estudo possam contribuir para o desenvolvimento de estrat?gias de incentivo ao processo de doa??o de ?rg?os e transplante renal

Cardiovascular diseases in the Czech Republic represent the main cause of death and significantly contribute to the sickness rate and premature disability. Possibilities of treatment of cardiovascular diseases keep developing increasingly these days. An important part is the follow up spa treatment as well as sufficiently performed effective cardio rehabilitation. The theoretical part characterizes functional examination of the lungs and stress tests in cardiology. Simultaneously it describes early spa treatment and defines quality of life. The aim of the diploma thesis, which deals with the vital capacity of the lungs, was to prove positive effect of early spa treatment on the vital capacity of the lungs and on improvement of quality of life, specifically with respect to positive perception of one´s overall physical health. Hypotheses - H1: An early spa therapy positively affects spirometry values. H2: Patients with an early spa therapy better perceive their overall physical health. A form of quantitative research was chosen, in order to verify the determined aims and hypotheses of the diploma thesis. A standardized international Short Form SF - 36 questionnaires on quality of life was used for the data collection. Spirometry was utilized for ascertaining objective functional parameters. Values of spirometry examination were used for comparison. 32 patients after cardiovascular surgery were included in the research, who were transferred to Lázně Poděbrady on the 6th - 8th day after the surgery, 22 of them being men (69%) and 10 women (31 %). The average age of patients under research was 66,06 + 11,48 years. The check group consisted of 10 healthy volunteers. 8 women (80 %) and 2 men (20 %) at the average age of 37,1 + 13,3 years were included in the research. It follows from the spirometry results measured before the heart surgery at IKEM cardio center that a difference in results between the second and third spirometry occurred. The second and third spirometrical examination is the period of time, when the respondent undergoes the early spa treatment. After the heart surgery spirometry values worsen and improve in the course of the spa therapy. The research showed that the perception of overall physical health after the heart surgery is subject to perception of pain, which negatively affected sense of overall perception of physical health. H1 was confirmed and H2 was not confirmed. In order to improve current situation, it would be suitable to devote not only to cardio rehabilitation but also to improvement of perception of pain, e.g. by means of psychotherapy (art therapy, music therapy?). It is also important to widen a possibility of outpatient cardio rehabilitation in each cardio center for patients after heart surgery.