Global ETD Search

31	Functional characterization of roles of histone deacetylases in the regulation of DNA damage response Yuan, Zhigang. January 2007 (has links) Dissertation (Ph.D.)--University of South Florida, 2007. / Includes vita. Includes bibliographical references. Also available online.
32	AKT function and human oncogenesis Park, Sungman. January 2007 (has links) Dissertation (Ph.D.)--University of South Florida, 2007. / Includes vita. Includes bibliographical references. Also available online.
33	Large scale protein purification of Wt1 ZF(-/-), Wt1 ZF(-/+), and Ciao-1 Bitschy, Ami 15 December 2008 (has links) WT1 has two main isoforms: WT1(-KTS) and WT1(+KTS). Both are known to bind to a DNA consensus sequence with different affinities, and are thus postulated to play overlapping but distinct functional roles in the cell. WT1 is also known to bind to certain RNA moieties as well as to various protein partners (e.g. Ciao-1). This study focuses on the development of large scale protein purification protocols for WT1 zinc finger (ZF) proteins as well as Ciao-1. By using a combination of his-tag affinity and size exclusion chromatography we were able to purify milligram quantities of these proteins. It was also the intention to obtain crystals of the WT1 ZF protein in complex with any one of its known binding partners, in particular the protein Ciao-1 (a WD40 protein) and the 14 mer consensus sequence of DNA (known as WTE). In conjunction with structural studies it was determined that a previously made SELEX RNA library was not selective for the (+KTS) isoform of WT1 ZF, and therefore no RNA candidate could be identified for future structural studies. Protein purification Wilms tumor suppressor protein Ciao-1
34	Mdm2 phosphorylations : characterization and applications / Malmlöf, Maria, January 2007 (has links) Lic.-avh. (sammanfattning) Stockholm : Karolinska institutet, 2007. / Härtill 2 uppsatser.
35	p63 and potential p63 targets in squamous cell carcinoma of the head and neck / Boldrup, Linda, January 2008 (has links) Diss. (sammanfattning) Umeå : Univ., 2008. / Härtill 4 uppsatser.
36	Study of the roles of LRBA in cancer cell proliferation and SHIP-1 in NK cell function / Gamsby, Joshua John. January 2005 (has links) Dissertation (Ph.D.)--University of South Florida, 2005. / Includes vita. Includes bibliographical references. Also available online in PDF format.
37	Functional characterization of roles of histone deacetylases in the regulation of DNA damage response Yuan, Zhigang. January 2007 (has links) Dissertation (Ph.D.)--University of South Florida, 2007. / Title from PDF of title page. Document formatted into pages; contains 87 pages. Includes vita. Includes bibliographical references.
38	AKT function and human oncogenesis Park, Sungman. January 2007 (has links) Dissertation (Ph.D.)--University of South Florida, 2007. / Title from PDF of title page. Document formatted into pages; contains 128 pages. Includes vita. Includes bibliographical references.
39	Multiple modes of MDMX regulation affect p53 activation Gilkes, Daniele M. January 2008 (has links) Dissertation (Ph.D.)--University of South Florida, 2008. / Title from PDF of title page. Document formatted into pages; contains 197 pages. Includes vita. Includes bibliographical references.
40	Mechanisms of P53-mediated apoptosis Harms, Kelly Lynn. January 2007 (has links) (PDF) Thesis (Ph.D.)--University of Alabama at Birmingham, 2007. / Title from first page of PDF file (viewed on June 24, 2009). Includes bibliographical references.

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