The Twin Transitions (TT) concept highlights the interconnection between the green transition, geared toward achieving climate goals, and the digital transition, aimed at disseminating digital technologies and infrastructures. These objectives are fundamental for the long run competitiveness of economic systems. Even though various EU strategic documents and a part of the scientific literature assume the two transitions to be mutually reinforcing, the effective sustainability of the TT is endangered by two issues of environmental nature: the dependence of modern technologies on specific mineral resources and the management of end-of-life technologies, that is electronic waste. Circular Economy (CE) strategies, ultimately aimed at decoupling techno-economic systems from the use of natural resources and at a minimization of human-induced environmental impacts, emerge as a tool to address both issues. Throughout the thesis, this overarching research theme has evolved into three lines of activity: 1) analysis of the relationship between recent technological trajectories and mineral resources consumption; 2) review of the literature on Extended Producer Responsibility (EPR) to investigate its rationale, policy makers expectations and, focusing on the specific case of electronic waste, its impacts in environmental and innovation terms; 3) empirical analysis of the relationship between EPR on batteries and international trade of waste. The project embraces the multidisciplinary and multidimensionality nature of sustainability analysis, by linking various streams of literature (Innovation studies, Ecological Economics, International Economics, Environmental Economics) and types of data (international trade, patents, waste management, resources extraction, material composition of technologies, scientific production). Ultimately, the project elucidates how both market-driven and policy-led CE strategies can engender structural changes capable of driving, at least partially, the Twin Transition dynamics toward achieving effective sustainability outcomes.