Since the Federal Communication Commission released the unlicensed 3.1-10.6 GHz frequency band for commercial use in early 2002, the ultra wideband (UWB) has developed from an emerging technology into a mainstream research area. The UWB technology, which utilizes wide spectrum, opens a new era of possibility for practical applications in radar sensing, one of which is the human vital sign monitoring. The aim of this thesis is to study and research the possibility of a new generation humanrespiration monitoring sensor using UWB radar technology and to develop a new prototype of UWB radar sensor for system-on-chip solutions in CMOS technology. In this thesis, a lowpower Gaussian impulse UWB mono-static radar transceiver architecture is presented. The UWB Gaussian pulse transmitter and receiver are implemented and fabricated using 90nm CMOS technology. Since the energy of low order Gaussian pulse is mostly condensed at lower frequency, in order to transmit the pulse in a very efficient way, higher order Gaussian derivative pulses are desired as the baseband signal. This motivates the advancement of the design into UWB high-order pulse transmitter. Both the Gaussian impulse UWB transmitter and Gaussian higher-order impulse UWB transmitter take the low-power and high-speed advantage of digital circuit to generate different waveforms. The measurement results are analyzed and discussed. This thesis also presents a low-power UWB mono-static radar transceiver architecture exploiting the full benefit of UWB bandwidth in radar sensing applications. The transceiver includes a full UWB band transmitter, an UWB receiver front-end, and an on-chip diplexer. The non-coherent UWB transmitter generates pulse modulated baseband signals at different carrier frequencies within the designated 3-10 GHz band using a digitally controlled pulse generator. The test shows the proposed radar transceiver can detect the human respiration pattern within 50 cm distance. The applications of this UWB radar sensing solution in commercialized standard CMOS technology include constant breathing pattern monitoring for gated radiation therapy, realtime monitoring of patients, and any other breathing monitoring. The research paves the way to wireless technology integration with health care and bio-sensor network.