This document reflects the results of evaluating three computational methods to analyse the fatigue life of components mounted on the cylinder block; two currently in use at Scania and one that has been further developed from its previous state. Due to the cost of testing and the exponential increase in computational power throughout the years, the cheaper computational analyses have gained in popularity. When a component is mounted in a fairly complex assembly such as an engine, simplifications need to be made in order to make the analysis as less expensive as possible while keeping a high degree of accuracy. The methods of Virtual Vibrations, VROM and VFEM have been evaluated and compared in terms of accuracy, computational cost, user friendliness and general capacities. Additionally, the method VFEM has been further developed and improved from its previous state. A in-depth investigation regarding the differences of the methods has been conducted and improvements to make them more efficient are suggested herein. The reader can also find a decision matrix and recommendations regarding which method to use depending on the general characteristics of the component of interest and other factors. Two components, which differ in complexity and mounting nature, have been used to do the research.