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The effects of ß-catenin on MMP-2 and MT1-MMP expression in endothelial cells /Doyle, Jennifer L. January 2005 (has links)
Thesis (M.Sc.)--York University, 2005. Graduate Programme in Kinesiology and Health Science. / Typescript. Includes bibliographical references (leaves 80-94). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://gateway.proquest.com/openurl?url%5Fver=Z39.88-2004&res%5Fdat=xri:pqdiss &rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:MR11777
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Prognostic significance of circulating vascular endothlial [sic] growth factor in patients with hepatocellular carcinomaPoon, Tung-ping, Ronnie. January 2006 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2006. / Title proper from title frame. Also available in printed format.
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The upregulation of VEGFR1 by mechanical stretch and shear stress in endothelial cells /Fudalewski, Tomasz S. January 2009 (has links)
Thesis (M.Sc.)--York University, 2009. Graduate Programme in Kinesiology. / Typescript. Includes bibliographical references (leaves 75-109). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:MR51528
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Prognostic significance of circulating vascular endothlial [sic] growth factor in patients with hepatocellular carcinomaPoon, Tung-ping, Ronnie., 潘冬平. January 2006 (has links)
published_or_final_version / abstract / Surgery / Doctoral / Doctor of Philosophy
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Regulation of vascular endothelial growth factor by ginsenoside RG1 inhuman endothelial cellsNg, Hoi-man., 伍凱敏. January 2009 (has links)
published_or_final_version / Biological Sciences / Master / Master of Philosophy
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Effect of anticardiolipin antibodies on vascular endothelial growth factor : a secretion from human umbilical vein endothelial cells / Title on signature form: Effect of anticardiolipin antibodies on vascular endothelial growth factor : a secretion from human umbilical vein endothelial cellsElawam, Noura Otman 03 May 2014 (has links)
Antiphospholipid syndrome (APS) is an autoimmune disorder defined as the persistent presence
of antiphospholipid antibodies (aPL) associated with recurrent thrombotic events and/or fetal
loss. The mechanisms for fetal loss in this syndrome have not yet been clearly explained,
although several hypotheses based on experimental data have been put forward. It has been
shown that proliferation of human umbilical vein endothelial cells (HUVECs) decreased
significantly in cultures that contained sera positive for anticardiolipin antibody activity collected
from patients with recurrent fetal loss. We explored the effect of ACAs on Vascular Endothelial
Growth factor- A (VEGF-A) secretion of cultured HUVECs. VEGF appears to be the most
endothelial cell-specific and unequivocal angiogenic factor. In vitro, VEGF causes endothelial
cell proliferation and migration; in vivo, it is potently angiogenic and causes vascular
permeability. We determined the effect of ACA IgG 40μg/ml and 80μg/ml on VEGF secretion
using ELISA. The results were measured in mean ± SD and expressed in pg of VEGF/5 x 10⁴
cells. P ≤ 0.05 considered significant as compared to control. The results showed that ACA
increases VEGF-A secretion and/or may bind at VEGF-A binding sites. This finding may be
useful for finding therapies for patients with recurrent miscarriages. / Access to thesis permanently restricted to Ball State community only. / Department of Physiology and Health Science
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Regulation of vascular endothelial growth factor by ginsenoside RG1 in human endothelial cellsNg, Hoi-man. January 2009 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2010. / Includes bibliographical references (leaves 81-93). Also available in print.
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The role of vascular endothelial growth factor as a regulator of secretion in the human oviduct. / CUHK electronic theses & dissertations collectionJanuary 2004 (has links)
Both VEGF and its receptor proteins were localized by immunostaining technique in the luminal epithelium, smooth muscle cells and blood vessels within the oviduct. Moreover, by means of semi-quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) techniques, it has been demonstrated that mRNA of VEGF and its receptors in both healthy and diseased oviduct is expressed preferentially at the time and place where the amount of oviduct fluid is prominent. This supports the notion that VEGF may be a regulator of oviductal secretion. This thesis has consistently demonstrated a modulation pattern of flt-1 expression that is similar to its ligand VEGF in both physiological and pathological conditions. This suggests that flt-1 may be the main receptor responsible for the action of VEGF in the oviduct. As illustrated in both the in-vivo and in-vitro models, the expression of VEGF and flt-1 in the human oviduct is stimulated directly by gonadotropins without the influence of ovarian sex hormones. / Increased knowledge on the regulatory mechanisms of oviductal fluid formation, the first environment that human embryos are exposed to, will be valuable from the clinical management point of view. / Oviductal fluid is a complex mixture of plasma-derived constituents and proteins synthesized by the oviduct epithelium. It has been postulated that vascular endothelial growth factor (VEGF), a known permeability promoter, may be an important regulator of oviductal fluid secretion by stimulating vascular permeability and so serum transudation. However, little is known about the expression of VEGF in the human oviduct. This thesis investigated the modulation of VEGF and its receptors (flt-1 and KDR) in the healthy oviducts, from fertile women undergoing tubal sterilization for unwanted fertility or hysterectomy for benign gynecological conditions, as well as in the hydrosalpinges from sterile women undergoing salpingectomy before the treatment of in-vitro fertilization and embryo transfer. / Lam Po Mui. / Adviser: Christopher J. Haines. / Source: Dissertation Abstracts International, Volume: 73-01, Section: B, page: . / Thesis (M.D.)--Chinese University of Hong Kong, 2004. / Includes bibliographical references (leaves 147-179). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [201-] System requirements: Adobe Acrobat Reader. Available via World Wide Web.
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Exercise and angiogenic growth factors in human skeletal muscle /Gustafsson, Thomas, January 2005 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2005. / Härtill 5 uppsatser.
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Studies of VEGF-B and novel PDGFs in tumorigenesis and angiogenesis /Li, Hong, January 2004 (has links)
Diss. (sammanfattning) Stockholm : Karol inst., 2004. / Härtill 4 uppsatser.
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