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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
101

Epigenetic Basis for Heterogeneity in VCAM-1 Gene Expression Patterns in Cytokine Activated Vascular Endothelium

Jamal, Alisha Noorin 01 January 2011 (has links)
Vascular cell adhesion molecule-1 (VCAM-1) is a cytokine-activated protein present on endothelial cells (ECs). Our laboratory has provided evidence that DNA methylation, a mark associated with gene silencing, is fundamental for regulating VCAM-1 expression. First, we showed that RNA polymerase II, preferentially associates with VCAM-1 hypomethylated alleles. This finding was confirmed using fluorescence-activated cell sorting (FACS) to sort populations of cytokine-activated ECs with high vs. low cell surface VCAM-1 expression. We found that ECs with high VCAM-1 expression were hypomethylated at the promoter. We then went on to show that populations of cells generated from single ECs exhibit differential VCAM-1 methylation from one another, and from the original founder population. Intriguingly, our data shows that VCAM-1 mRNA levels differ between the clones, and correlate with the observed differences in DNA methylation. Taken together, this data provides exciting evidence that DNA methylation is important in the regulation of VCAM-1 gene expression.
102

Role of shear stress in angiopoietin-2-dependent neovascularization:

Tressel, Sarah Lynne. January 2008 (has links)
Thesis (Ph. D.)--Biomedical Engineering, Georgia Institute of Technology, 2008. / Committee Chair: Jo, Hanjoong; Committee Member: McIntire, Larry; Committee Member: Nie, Shuming; Committee Member: Taylor, Robert; Committee Member: Weyand, Cornelia.
103

Relationship between psychological status and vascular function in subjects with and without cardiovascular diseases

Chen, Hua, January 2008 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2008. / Includes bibliographical references (leaf 109-129) Also available in print.
104

Modulation of endothelium-dependent contractions by chronic inhibition of nitric oxide synthase in the rat aorta

Qu, Chen, January 2008 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2008. / Includes bibliographical references (leaves 96-112) Also available in print.
105

Cellular mechanisms of effects of sphingosine 1-phosphate on vascular endothelial barrier

Xu, Mei, January 2008 (has links)
Thesis (Ph. D.)--West Virginia University, 2008. / Title from document title page. Document formatted into pages; contains ix, 109 p. : ill. (some col.). Includes abstract. Includes bibliographical references.
106

Relationship between psychological status and vascular function in subjects with and without cardiovascular diseases /

Chen, Hua, January 2008 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2008. / Includes bibliographical references (leaf 109-129) Also available online.
107

Regulation of inflammtory [sic] activation in endothelial cells by PIN1

Liu, Tongzheng, January 2009 (has links)
Thesis (Ph. D.)--Ohio State University, 2009. / Title from first page of PDF file. Includes bibliographical references (p. 202-241).
108

Endothelium-dependent hyperpolarization and relaxation of vascular smooth muscle

Zygmunt, Peter. January 1995 (has links)
Thesis (doctoral)--Lund University, 1995. / Added t.p. with thesis statement inserted.
109

Endothelium-dependent hyperpolarization and relaxation of vascular smooth muscle

Zygmunt, Peter. January 1995 (has links)
Thesis (doctoral)--Lund University, 1995. / Added t.p. with thesis statement inserted.
110

Interaction of vascular structure and function with myocardial ischaemia and survival /

Fathi, Robert B. January 2004 (has links) (PDF)
Thesis (Ph.D.) - University of Queensland, 2003. / Includes bibliography.

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