In a workplace marked by increasing change and competing commitments, business leaders require an increased understanding of alternative work programs. Utilizing spillover theory, motivator-hygiene theory, and adaptive structuration theory, this single case study was an exploration of the strategies that business leaders use for flexible work schedules and virtual work programs. The population consisted of 3 managerial business executives and 6 employees within a midwestern United States division of a global blood management solutions firm. The data collection process included a series of semistructured interviews, a focus group, and the assessment of company documentation. Methodological triangulation identified 5 emerging themes: program assessment and monitoring, standard set of virtual working hours, remote office setup, increased virtual communication, and promotion of quality of life. The transferability of this single case study remains with the reader and future researchers to determine. Future researchers may discover that the findings contribute to social change by better preparing organizations for success while simultaneously positioning individuals to attain optimum balance across life and work responsibilities.