Background Number of patients treated with medicine that has an anticoagulation character is constantly increasing. Chronic atrial fibrillation is the most common diagnosis being treated, but other diagnoses such as venous thrombosis), pulmonary embolism, stroke, coronary stent thrombosis and arterial thrombosis treated. There are a variety of anticoagulant drugs. In Sweden Warfarin is used as standard medicine for oral anticoagulation therapy. Purpose The purpose of this study is to examine and reflect nurses' experiences of working on anticoagulation clinic, and if he / she claims to have access to the necessary skills and resources to carry out a safe care. Design The study has a qualitative design with semi-structured interviews which were analyzed with an inductive approach. The interviews included six respondents. Findings The results showed that nurses who worked at anticoagulation Clinics had no specific training to operate these clinics. Respondents felt that they had obtained their knowledge through practical experience. However, previous research and Welfare guidelines emphasize the importance of continuous training. Even The National Board of Health and Welfare in Sweden requires that nurses should have significant skills to be able to provide good and safe care with high quality. Conclusion From these results it was concluded that the nurses who worked in anticoagulation clinics felt that they were able to do their work even though they had no specific training. However they considered that a basic theoretical knowledge could contribute to a more secure feeling regarding patient safety. Keywords Wafarinmonitoring, patient safety, Warfarin, Nurse