The main goal of this study is to examine the relationship between weight control expectancies, weight concerns, smoking rate and perceived likelihood of smoking in the future among Spanish adolescents. Specifically, I intend to explore the potential moderator role of weight concerns on the relationship between weight control expectancies and smoking rate, as well as between weight concern and perceived likelihood of smoking in the future. Additionally, I want to investigate the possible meditational role of weight control expectancies on the relationship between weight concerns and smoking rate and likelihood of smoking in the future, respectively. The participants were 311 Spanish adolescents (M = 15.20; SD = 1.63; 174 female and 137 male) from schools in Alicante, Spain. The students completed questionnaires regarding smoking history and status. They also responded to questions regarding smoking expectancies and weigh concerns. Results suggested differences between smokers and nonsmokers in weight control expectancies and fear of fatness regardless of gender. The moderator model of weight concerns was not supported by findings. The results prove the meditational role of weight control expectancies on the relationship between fear of fatness and smoking rate, as well as between fear of fatness and perceived likelihood of smoking in the future. Implications, directions for future research and limitations of the study are discussed.