Work zones create one of the most challenging environments for drivers. Implementing work zones on urban freeways creates many issues, especially with respect to mobility. Decisions made regarding the work zone should be informed by quantitative data, collected in work zones, to ensure that the mobility impacts of the work zone treatments implemented are mitigated. A new decision-making process, which addresses the shortcomings in the current decision-making processes, was developed through the course of this research. The new process incorporates a Performance Measure/Treatment matrix, which recommends multiple performance measures, each of which is chosen to measure the mobility impacts particular to a specific work zone implementation. Most importantly, the revised decision-making process incorporates a feedback loop. Quantitative data collected in work zones is analyzed after the work zone is complete, to determine the impacts specific decisions had on mobility in the work zone. The lessons learned in previous work zones are then incorporated into the decision-making process, lessening the mobility impacts of future work zones. This thesis develops the new decision-making process, and examines the issues with the application of the process.