This thesis arose out of my professional engagement as a therapist, with people suffering depression, and from my recognition of the significance of such people’s workplace experience in times of significant workplace change. Worker depression is now widely identified as a significant and growing problem by employers, by governments and by international authorities such as the World Health Organisation. By the end of the 20th century, it had become a significant site for policy, leading to the collection of data and the development of management ‘tools’ at all these levels. Actions formed by such new policy range from workplace interventions to the establishment of government-funded bodies, such as beyondblue and the Black Dog Institute in Australia, charged with both research and information dissemination. An understanding of the context in which depression is increasing requires an exploration of two 20th century phenomena: on the one hand, the changing workplace of the advanced capitalist societies; and on the other, the ways in which depression itself has come to be diagnosed and treated, and consequently understood, as a medical phenomenon. There is a substantial literature on the contemporary workplace, and on the diagnosis, treatment and management of depression. Very little is available, however, dealing with the experience of individual workers who have been diagnosed with depression. This is the area the thesis is concerned to explore. In order to undertake this task, two significant methodological moves have been made, away from the ‘realist’ orientation of much of the available literature. The ‘genealogical’ move, drawing on Foucault, is the move concerned to understand how things are as they are and not otherwise, to ask questions such as: How has depression come to be a more and more common diagnosis in the late 20th - early 21st centuries? What is it about workers’ experience of the workplace that is making such diagnoses more likely? Might it be the case that more workers are increasingly unhappy and that unhappiness, particularly manifested somatically, through bodily ‘symptoms’, is increasingly likely to be diagnosed and treated medically, as depression? The ‘discursive’ move, drawing on Foucault, together with Nikolas Rose and Judith Butler, is the move that works with the understanding that selves are not simply given, existing autonomously. Rather, persons are constituted as selves – as subjects – in and through their active participation in the social worlds they come to inhabit. The mechanisms of this participation are the characteristic ways of acting and speaking – the discourses – of social institutions. Learning such discourses involves not only learning how to act appropriately but also to become a certain kind of self. For workers in the neoliberal workplace, this means learning to be the autonomous, flexible worker of overt requirements while simultaneously learning to live with increased demands for hours of work and levels of work output, together with escalating levels of surveillance. It is not surprising that many workers experience this workplace as increasingly stressful. Such stress, when medically diagnosed and treated as ‘depression’, offers a new kind of subject position to those affected. The heart of the thesis is an interview study which explores the narrative stages a set of workers diagnosed as depressed detail as they account for their progressive ‘resubjectification’ as depressed workers. Five stages, involving the narrative positioning of different selves or subject positions, are identified from detailed readings of the interview data: these are the narrating of psychologising, internalising, somatising, medicalising and pharmacologising positionings. The identification and naming of these stages draws substantially on the work of Nikolas Rose and his identification of key 20th century selves. The identification of these as narrative or discursive stages in the retrospective reconstruction of resubjectified selves is the original contribution of this thesis.