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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Mxr1p is a Global Regulator of Multiple Metabolic Pathways in the Methylotrophic Yeast Pichia Pastoris

Sahu, Umakant January 2016 (has links) (PDF)
The present study is aimed at examining the ability of Pichia pastoris to utilize acetate and amino acids as the sole sources of carbon. We demonstrate that the zinc finger transcription factor Mxr1p, which is a positive regulator of methanol metabolism, is also required for the growth of P. pastoris in media containing acetate or amino acids as the sole source of carbon. We have identified the target genes of Mxr1p in cells cultured in media containing acetate or amino acids as the sole carbon source. We conclude that Mxr1p is a global regulator of multiple metabolic pathways in P. pastoris.

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