Recently, many industries pursue the goal of automatic high-speed assembly and manufacturing. So how to meet the requirement of high-precision and high-speed automatic assembly equipment is an important issue. In automatic assembly equipment, the inappropriate acceleration or deceleration motion will cause unsuitable inertia force and vibration to the positioning table. In order to reach the high production efficiency level, the problems of shortage of motor power, poor positioning accuracy, residual vibration, and noise shall be analyzed and solved. In previous researches, the researchers all devote to study acceleration and deceleration based on symmetrical time chart. In this paper, we change the accelerating and decelerating phase to reduce inertia force and decrease residual vibration of point-to-point motion. The system model is built to simulate dynamic response of the system. Through the results of simulation and experiment, we will discover the relations between the properties of motion and residual vibration about the high-speed positioning tables. It is expected to improve residual vibrations and design motion profiles according to those effective transient response control charts.