Submitted by Cristiane Chim (cristiane.chim@ucpel.edu.br) on 2016-12-05T12:21:14Z No. of bitstreams: 2 fernanda lauermann1 (1).pdf: 392185 bytes, checksum: 4fac0ee2e4935d3526bbdf42f7a635bf (MD5) fernanda lauermann1 (2).pdf: 37349 bytes, checksum: de3f0dae8ca328b17261c84547e4e07a (MD5) / Made available in DSpace on 2016-12-05T12:21:14Z (GMT). No. of bitstreams: 2 fernanda lauermann1 (1).pdf: 392185 bytes, checksum: 4fac0ee2e4935d3526bbdf42f7a635bf (MD5) fernanda lauermann1 (2).pdf: 37349 bytes, checksum: de3f0dae8ca328b17261c84547e4e07a (MD5) Previous issue date: 2015-07-19 / Background: Acne vulgaris is a pilosebaceous follicle disorder that affects more than 85% of adolescents in some degree, and frequently causes psychological distress that persists into adulthood due to scarring. There is lack of information about post acne scarring pathogenesis, and its treatment remains a challenge. Objectives:Background: Acne vulgaris is a pilosebaceous follicle disorder that affects more than 85% of adolescents in some degree, and frequently causes psychological distress that persists into adulthood due to scarring. There is lack of information about post acne scarring pathogenesis, and its treatment remains a challenge. Objectives: To describe the characteristics and distribution patterns of acne scarring and associated factors in young males, from a representative sample of the population in a city of southern Brazil. Methods: A cross-­‐sectional study was undertaken during the presentation for the military service, which is compulsory for all males when they turn eighteen years old. A questionnaire was applied with topics on diet, smoking habit, ethnicity, family structure, socio-­‐economic level and specific questions about active acne and its scars. Dermatologists conducted the clinical examination. Results: A total of 2.201 male adolescents were enrolled in the study. The overall prevalence of acne scarring was 22%. The malar region was the most frequently affected: more than eighty percent of participants had scars at this site, followed by the frontal (31.5%), back trunk (17%), anterior chest (8.2%) and mentonian region (6.4%). Correlation between the intensity of clinical acne and the presence of scars was found, but no association was observed when variables such as education level, smoking, ethnicity, obesity and socio-­‐economic status were accounted for. Conclusions: This is the first study to investigate a correlation between acne scarring and factors such as socio-­‐economic status and education level. Nevertheless, larger, population-­‐based studies are needed to settle this question. The direct relation 16 between acne severity and scarring indicate that prompt and effective treatment is the best form of scarring reduction. To describe the characteristics and distribution patterns of acne scarring and associated factors in young males, from a representative sample of the population in a city of southern Brazil. Methods: A cross-­‐sectional study was undertaken during the presentation for the military service, which is compulsory for all males when they turn eighteen years old. A questionnaire was applied with topics on diet, smoking habit, ethnicity, family structure, socio-­‐economic level and specific questions about active acne and its scars. Dermatologists conducted the clinical examination. Results: A total of 2.201 male adolescents were enrolled in the study. The overall prevalence of acne scarring was 22%. The malar region was the most frequently affected: more than eighty percent of participants had scars at this site, followed by the frontal (31.5%), back trunk (17%), anterior chest (8.2%) and mentonian region (6.4%). Correlation between the intensity of clinical acne and the presence of scars was found, but no association was observed when variables such as education level, smoking, ethnicity, obesity and socio-­‐economic status were accounted for. Conclusions: This is the first study to investigate a correlation between acne scarring and factors such as socio-­‐economic status and education level. Nevertheless, larger, population-­‐based studies are needed to settle this question. The direct relation 16 between acne severity and scarring indicate that prompt and effective treatment is the best form of scarring reduction. / A acne vulgar é uma desordem da unidade pilossebácea com prevalência de 85-90% em adolescentes (1,2). Um fator que adiciona impacto e importância a patologia é a predominância nesta faixa etária, uma fase da vida que por si só já carrega muitas preocupações com autoestima e imagem. Na grande maioria dos casos a doença cessa aos 23-25 anos de idade, mas em até 14% dos indivíduos o quadro pode persistir (3), e essaobservação contraria a afirmação de que a acne é exclusivamenteuma afecção autolimitada própria da adolescência. Em tais casos, a tendência atual é considerar o distúrbio como uma doença crônica (4). Mesmo nos casos em que há melhora ou resolução do quadro, o impacto emocional pode persistir devido às cicatrizes da acne, que ocorrem precocemente, e afetam 95% dos pacientes com a patologia. Até o momento, a prevalência e fatores associados dessas sequelas não foram extensivamente estudados. Layton et al (5)relacionaram a gravidade das cicatrizes com a severidade e demora no início do tratamento da acne. Entre suas formas de apresentação, tanto a acne pápulo-pustulosa quanto a nódulo-cística podem causar cicatrizes. O impacto emocional da acne e suas cicatrizes é bem documentado, sendo causa frequente de distúrbios psicológicos. A doença já foi apontada como importante fator de risco para suicídio, e estudos sugerem que o impacto emocional é comparável ao de doenças sistêmicas como diabetes, asma, artrite e epilepsia (6,7). O tratamento das cicatrizes de acne é desafiador. Há inúmeros trabalhos sobre diferentes técnicas, invasivas ou não e com variáveis custos. A dificuldade também reside na comparação entre as várias opções de tratamento pois há falta de consenso na nomenclatura e classificação das lesões, e da mesma forma estudos com boa qualidade metodológica são escassos(8). O presente estudo objetiva trazer novas evidências sobre fatores associados a acne e cicatrizes, tendo como vantagem a avaliação dos 4 participantes por profissionais experientes em dermatologia. A maioria dos trabalhos utiliza apenas questionários auto-referidos, o que já foi demonstrado ter baixa sensibilidade e especificidade para definição de casos (9).