Aim: The aim of this study was to evaluate the accuracy of the Wirele-X (Forum Tec, Ashkelon, Israel), a new Bluetooth-enabled electronic apex locator (EAL). The accuracy of the Wirele-X and the Root ZX II (J. Morita, Tokyo, Japan) was compared in vitro using an alginate model. Materials/Methods: Thirty-one extracted single-rooted human teeth with mature apices were decoronated at the CEJ. Under 10X magnification, actual canal lengths (ACL) were determined. The teeth were embedded in alginate and electronic canal length measurements were obtained using the Root ZX II and Wirele-X EALs. Each tooth was measured three times with both EALs. A blinded examiner measured each file with a digital micrometer to the nearest 0.01 mm. Differences between ACLs and the average measurements from the EALs were compared with Student's t test for related samples. Results: The average distance from the file tip to the apical foramen (AF) was -0.11 mm (±0.16) and -0.07 mm (±0.21) for the Root ZX II and Wirele-X systems, respectively. There were no statistically significant differences between the two apex locators in their ability to locate the AF (p > 0.05). Conclusions: Both the Wirele-X and the Root ZX II provided a high level of accuracy and reliability in locating the AF.