The field of Adaptive Music Technology is rapidly expanding and evolving. While there have been a number of theses and dissertations devoted to the study of new computer music instrument design for persons with disabilities, there is, as yet, no comprehensive study of all of the instruments that have been developed, along with recommendations for how to develop future musical instruments given rapid changes in technology. In this thesis, a comprehensive literature review of previous instruments developed is presented, along with personal interviews of developers where literature has not yet been published about a given instrument. Then recommendations for future development of instruments based on this information are presented. Finally, a case study of the development of one such instrument using the Microsoft Kinect is undertaken, and observations and conclusions based on this research are drawn. / Graduate