Vertical alignment liquid crystal display has the advantages of wide view angle, high contrast and good response time. Today vertical alignment liquid crystal display get flourishing development, and Multi-Domain Vertical Alignment (MVA) technology is progressive. In this report we would find an alignment materiel which could be fabricated easily, low cost and good E-O characteristic. The use of dimenthysiloxane (PDMS) in fabrication of microfluidic channels technology in biotechnology has the advantages of characteristics foregoing. In this study PDMS was used as LC vertical alignment materiel. We used the MVA structure and ASV structure to align LC direction because PDMS cannot be rubbed. In experiment we found that PDMS exhibited different surface energies when it was baked in different temperature. The results of measuring the pre-tilt angle in the different surface energy conditions are similar. ASV LC samples were fabricated using PDMS alignment layer. MVA LC cells were made using high viscosity PDMS. We found the characteristic of paper white at CIE chromaticity diagram in the ASV LC sample without any color filter and color correction technology.