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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.

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Showing 1 to 2 of 2 (0.081 seconds)

Spelling suggestions: "subject:"aliphatischen amine"" "subject:"aliphatischen imine""

1

Toxicity of aliphatic amines on the embryos of zebrafish Danio rerio - experimental studies and QSAR / experimental studies and QSAR / Toxizität aliphatischer Amine auf die Embryonen des Zebrabärblings Danio rerio - experimentelle Studien und QSAR

Brust, Kristin 09 July 2002 (has links) (PDF)
The toxicity of 36 aliphatic amines on the embryos of the zebrafish Danio rerio were investigated. The DarT (Danio rerio Toxicity assay) was used to determine the lethal concentrations within a 48 h static acute toxicity test. A QSAR (Quantitative Structure-Activity Relationship) was performed using the LC50 values and molecular descriptors such as lipophilicity, maximum positive charge on hydrogen atom and the effective diameter of the molecule. In general, the toxicity of primary and secondary amines could be described by the lipophilicity as descriptor. The toxicity of the tertiary amines tested could be only described by a bilinear regression model. Further, regression models for other aquatic species such as the fathead minnow Pimephales promelas, Daphnia magna and Tetrahymena pyriformis showed that the toxicity of each species is a good predictor for each other.
Danio rerio
QSAR
Toxizität
aliphatische Amine
Danio rerio
QSAR
aliphatic amines
toxicity
ddc:32
rvk:WR 4200
Aliphatische Verbindungen
Amine
QSAR
Toxizität
Zebrabärbling
2

Toxicity of aliphatic amines on the embryos of zebrafish Danio rerio - experimental studies and QSAR: experimental studies and QSAR

Brust, Kristin 05 June 2002 (has links)
The toxicity of 36 aliphatic amines on the embryos of the zebrafish Danio rerio were investigated. The DarT (Danio rerio Toxicity assay) was used to determine the lethal concentrations within a 48 h static acute toxicity test. A QSAR (Quantitative Structure-Activity Relationship) was performed using the LC50 values and molecular descriptors such as lipophilicity, maximum positive charge on hydrogen atom and the effective diameter of the molecule. In general, the toxicity of primary and secondary amines could be described by the lipophilicity as descriptor. The toxicity of the tertiary amines tested could be only described by a bilinear regression model. Further, regression models for other aquatic species such as the fathead minnow Pimephales promelas, Daphnia magna and Tetrahymena pyriformis showed that the toxicity of each species is a good predictor for each other.
info:eu-repo/classification/ddc/32
ddc:32

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