Thesis (M.E.E.)--University of Delaware, 2006. / Principal faculty advisor: Javier Garcia-Frias, Dept. of Electrical and Computer Engineering. Includes bibliographical references.

Thesis (Ph.D) -- McMaster University, 1997. / Includes bibliographical references (leaves 87-95). Also available via World Wide Web.

Diss. (sammanfattning) Stockholm : Karolinska institutet, 2001. / Härtill 4 uppsatser.

Diss. (sammanfattning) Stockholm : Karol. inst., 2001. / Härtill 4 uppsatser.

Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 5 uppsatser.

Diss. (sammanfattning) Stockholm : Karol. inst., 2001. / Härtill 5 uppsatser och 1 appendix.

Diss. (sammanfattning) Stockholm : Karol. inst., 2001. / Härtill 8 uppsatser.

Thesis (Ph. D.)--University of Washington, 2002. / Vita. Includes bibliographical references (leaves 135-139).

ODC activity of the altered proteins was measured and compared to that of the full length 461 amino acid containing ODC. Mouse ODC cDNA sequences were deleted from either 5' or 3' ends using exonuclease III and Mung Bean nuclease treatments. An internal deletion was obtained by Hinc II and Bcl I restriction endonuclease digestion of the full length ODC cDNA. Capped mRNAs were synthesized in vitro using the resulting deleted DNA as templates, and the protein was translated in vitro. The results indicate that the protein in which translation initiates at internal AUG start codons does not have any activity. The protein with 39 amino acids deleted from carboxy-terminus maintains 12% of the activity, while deletion of greater than 79 amino acids have no activity. An internal deletion from amino acid 290 to 331 and which may contain the suspected ornithine binding site has no activity. These results suggest that the entire amino acid sequence of mouse ODC is required for full activity of the enzyme.

by Sze-wan Man. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1997. / Includes bibliographical references (leaves 41-42). / Chapter Chapter 1 --- Introduction --- p.1 / Chapter Chapter 2 --- The probability model --- p.8 / Chapter 2.1 --- Introduction --- p.8 / Chapter 2.2 --- The coding system --- p.11 / Chapter 2.3 --- The likelihood estimates of hexamer codes --- p.13 / Chapter 2.4 --- A cross validation study --- p.15 / Chapter Chapter 3 --- An application of the likelihood ratio --- p.21 / Chapter 3.1 --- Introduction --- p.21 / Chapter 3.2 --- The Needleman-Wunsch algorithm --- p.21 / Chapter 3.2.1 --- Background --- p.21 / Chapter 3.2.2 --- The principle of the algorithm --- p.21 / Chapter 3.2.3 --- The algorithm --- p.23 / Chapter 3.3 --- Application of the structural information --- p.25 / Chapter 3.3.1 --- Basic idea --- p.25 / Chapter 3.3.2 --- Comparison between pairs of hexamer sequences --- p.25 / Chapter 3.3.3 --- The score of similarity of a pair of hexamer sequences --- p.26 / Chapter Chapter 4 --- Application of the modified Needleman-Wunsch algorithm --- p.27 / Chapter 4.1 --- The structurally homologous pair --- p.27 / Chapter 4.1.1 --- The horse hemoglobin beta chain --- p.28 / Chapter 4.1.2 --- The antartic fish hemoglobin beta chain --- p.29 / Chapter 4.2 --- Other proteins --- p.31 / Chapter 4.2.1 --- The acetylchoinesterase --- p.31 / Chapter 4.2.2 --- The lipase --- p.32 / Chapter 4.2.3 --- The two A and D chains of the deoxyribonuclease --- p.33 / Chapter 4.3 --- Evaluation of the significance of the maximum match --- p.36 / Chapter Chapter 5 --- Conclusion and discussion --- p.38 / References --- p.41 / Tables --- p.43