The purpose of this study was to (1) assess the reliability and validity of anger/hostility measures, (2) examine the relationship between anger/hostility and other negative emotions, and (3) examine the relationship between anger/hostility and health history. Sixty-five subjects were given the Buss Durkee Hostility Inventory (BDHI), the State-Trait Anger Expression Inventory (STAXI), the Profile of Mood States pomsS), the Clinical Analysis Questionnaire (CAQ), the State-Trait Anxiety Inventory (STAI), the Health and Wellness Attitude Inventory (HWAI), and a health questionnaire designed to provide information about past disease and alcohol/drug use. Overall, the BDHI and POMS displayed good test-retest reliability. All six of the global indices of anger/hostility intercorrelated at a significant level, thus demonstrating good concurrent validity. The six global measures of anger/hostility also correlated at a significant level with other negative emotions.