Anomalies of the teeth include a variety of expression such as: anodontia, hyperdontia, peg teeth. opalescent dentine, mottled enamel, and other imperfections of the teeth. This paper is concerned primarily with anodontia in human subjects, although other abnormalities of interest are mentioned. Insufficient datum is the principal difficulty encountered in determining the mechanism and means of transmission in human genetics. Small families, slow breeding, and inability to subject humans to experimentation account, in part, for this difficulty. The lack of reliable data is the second major difficulty in determining the mode of transmission. Often normal or unaffected members of a family are forgotten due to insignificance placed on them--thus an untrue pedigree is the result. The fact that one must rely on information from one or two members of a family lends itself to error. Therefore, an absolutely accurate determination of Mendelian ratios in human genetics would be impossible. This error, however, can be reduced by the gathering and compilation of large numbers of family pedigrees from which calculations can be made and results determined which will reveal the mode of transmission of various hereditary traits. With this view in mind, this paper is presented, first, to add several more cases to the literature, and, second, by analysis of the pedigrees to determine the possible modes of transmission of these anomalies.