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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Identificación y organización de los componentes celulares del timo de lubina (Dicentrarchus labrax)

Avilés Trigueros, Marcelino 17 May 1993 (has links)
Se realizó el estudio histológico del timo de lubina, con el fin de conocer la arquitectura del microambiente tímico y las relaciones estructurales de sus diferentes componentes. Las células linfoides sufren procesos de muerte celular programada por apoptosis, no descrita previamente en timo de peces; indicando la existencia de procesos de selección negativa durante su diferenciación intratímica. Existen células interdigitadas, no descritas previamente en peces. Hay áreas mielopoyéticas, con actividad eritropoyética y granulopoyética heterófila. La fragilidad de la barrera epitelial, que separa la cavidad branquial del parénquima tímico, puede verse incrementada por la presencia de macrófagos intraepiteliales y macrófagos con inmunoglobulinas de superficie. El transito de células sanguíneas a través de la capa de células epitelio-reticulares limitantes y de capilares sanguíneos indican la carencia de barrera hematotímica. Estos datos sugieren la existencia de procesos antígen o dependiente y la persistencia de funciones propias de órgano linfoide secundario en timo de lubina. / The histological study of the sea bass thymus was performed to know the architecture of the thymic microenvironment and the structural relationships of its different components. The lymphoid cells suffer processes of programmed cell death by apoptosis, not described previously in fish thymus, indicating the existence of negative selection processes during its intrathymic differentiation. There are interdigitating cells, which has not described before in fish. Exist myelopoiesis areas, with erythropoietic and heterophilic granulopoietic activity. The fragility of the epithelial barrier, that separates the branchial cavity from the thymic parenchyma, is increased by the presence of intraepithelial macrophages and macrophages with surface immunoglobulins. The traffic of blood cells across the layer of limiting reticular epithelial cells and blood capillaries indicate the lack of hemato-thymic barrier. This information suggests the existence of antigen dependent process and the p ersistence of own functions of secondary lymphoid organ in thymus of sea bass.

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