<p>Random numbers are required for cryptographic applications such as IT security products, smart cards etc. Hardwarebased random number generators are widely employed. Cryptographic algorithms are implemented on FieldProgrammable Gate Arrays (FPGAs). In this work a True Random Number Generator (TRNG) employed for spaceapplication was designed, investigated and evaluated. Several cryptographic requirements has to be satisfied for therandom numbers. Two different noise sources was designed and implemented on the FPGA. The first design wasbased on ring oscillators as a noise source. The second design was based on astable oscillators developed on a separatehardware board and interfaced with the FPGA as another noise source. The main aim of the project was to analyse theimportant requirement of independent noise source on a physical level. Jitter from the oscillators being the source forthe randomness, was analysed on both the noise sources. The generated random sequences was finally subjected tostatistical tests.</p>

Random numbers are required for cryptographic applications such as IT security products, smart cards etc. Hardwarebased random number generators are widely employed. Cryptographic algorithms are implemented on FieldProgrammable Gate Arrays (FPGAs). In this work a True Random Number Generator (TRNG) employed for spaceapplication was designed, investigated and evaluated. Several cryptographic requirements has to be satisfied for therandom numbers. Two different noise sources was designed and implemented on the FPGA. The first design wasbased on ring oscillators as a noise source. The second design was based on astable oscillators developed on a separatehardware board and interfaced with the FPGA as another noise source. The main aim of the project was to analyse theimportant requirement of independent noise source on a physical level. Jitter from the oscillators being the source forthe randomness, was analysed on both the noise sources. The generated random sequences was finally subjected tostatistical tests.

In recent years great advances in the field of biomedical engineering and organic electronics have been achieved. One promising application would be the regulation of blood glucose concentration in type 2 diabetes patients. This application would eliminate medication and would improve the standard of life. To achieve this goal a system is needed which receives information about the glucose concentration and reacts upon it. This output reaction could then be used to stimulate the body's own glucose regulation mechanisms. This thesis combined a glucose sensor with an artificial neuron to take the first step towards such a system. Two different artificial neurons, the Axon-Hillock neuron and the astable multivibrator, were characterized and examined upon their usability. The Axon-Hillock, build with organic electrochemical transistors, revealed that it could be applied for both regulating high and low blood glucose concentrations. The astable multivibrator, build with silicon-based transistors, was not as functional as the Axon-Hillock neuron but with more development it could become as good. The placement of the glucose sensor in the astable multivibrator circuit is essential parameter to consider. The results demonstrate that the examined system is functional and could become a part of a larger closed-loop system. Future tests on an animal model may demonstrate its viability as a treatment for type 2 diabetes.