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1	Vliv melatoninu na rytmické uvolňování ATP z organotypických kultur SCN potkana / The effect of melatonin on rhythmic ATP release from organotypic cultures of the rat SCN Dvořáková, Barbora January 2019 (has links) The rhythm of ATP accumulation is an one of examples of circadian rhythmicity which is demonstrated across the animal kingdom. It is located in the suprachiasmatic nucleus of hypothalamus, which is a centre of circadian clock and imposes rhytmicity on a whole organism. The question concering the ATP rhythm in an organotypic culture and the impact of melatonin on it has been discussing in this thesis. The synthesis of melatonin is regulated by the activity of the SCN and the hormon itself is known for its feedback on the SCN and a capability of regulating it. It has been shown that ATP rhythm is significantly inhibited under the constant control of melatonin and this inhibition is dose-dependent on a scale of 0,1-10 nM. In case of one-time applied melatonin in 4 p.m. there is no reduction in the accumulation of extracellular ATP but there is a phase shift in ATP rhythm. It has also been shown that ATP rhythm is inhibited and desynchronized under the control of tetrodotoxin which blocks an electric activity of neurons. These results show that melatonin is capable of inducing phase delay of ATP rhythm in SCN and reducing an amount of extracellular ATP, that the effect of melatonin is probably mediated by specific receptors and lastly that ATP rhythm is a result of cell-cell interaction between neurons...
2	Postnatale Gliogenese und Synaptogenese im somatosensorichen Coex der Maus / Postnatal gliogenesis and synaptogenesis in the somatosensory cortex of the mouse Nguyen, Thi Kim Loan 07 November 2011 (has links) No description available. 610 Medizin, Gesundheit Medicine Glia Synapse Gliogenese Synaptogenese;Neuron Astrozyt Somatosensorischer Cortex Maus glia synapse;gliogenesis synaptogenesis;neuron astrocyt somatosensory cortex mouse 44.34 44.35 44.49 MED 291: Anatomie MED 292: Histologie {Medizin}

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Vliv melatoninu na rytmické uvolňování ATP z organotypických kultur SCN potkana / The effect of melatonin on rhythmic ATP release from organotypic cultures of the rat SCN

Postnatale Gliogenese und Synaptogenese im somatosensorichen Coex der Maus / Postnatal gliogenesis and synaptogenesis in the somatosensory cortex of the mouse