Thesis (M.S.)--University of Wisconsin--Madison, 1966. / eContent provider-neutral record in process. Description based on print version record. Bibliography: l. 90-92.

Thesis (M. Sc.)--University of Hong Kong, 2000. / Includes bibliographical references (leaves 76-81).

Thesis (M.S.)--University of Wisconsin--Madison, 1982. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 47-52).

Thesis (M.P.H.)--University of Hong Kong, 2008. / Includes bibliographical references (p. 42-45).

Thesis (M.S.)--University of Delaware, 2008. / Principal faculty advisor: Jack Gelb, Dept. of Animal & Food Sciences. Includes bibliographical references.

Thesis (M.P.A.)--University of Hong Kong, 2003. / Includes bibliographical references (leaves 131-146). Also available in print.

Thesis (M.Med.Sc.)--University of Hong Kong, 2003. / Includes bibliographical references (leaves 31-34). Also available in print.

Thesis (Ph. D.)--University of Wisconsin--Madison, 1964. / Typescript. Vita. Description based on print version record. Includes bibliographical references (leaves 39-44).

Thesis (Ph. D.)--University of Hong Kong, 2010. / Includes bibliographical references (leaves 171-213). Also available in print.

Carotenoids are responsible for much of the bright yellow to red colours in animals and have been extensively studied as condition dependent signals in sexual selection. In addition to their function in coloration, carotenoids also play a crucial role in colour vision within certain lineages. Despite this, little is known about the genetic mechanisms underlying carotenoid based pigmentation. Recently, the gene CYP2J19 was strongly implicated in red ketocarotenoid pigmentation for coloration and colour vision within two lineages of song birds (the zebra finch and the red factor canary). Here, I extend the investigation of the function of CYP2J19 in colour vision and red coloration amongst reptiles. I suggest that the original function of CYP2J19 was in colour vision and that it has been independently co-opted for red coloration within certain red lineages. Using a combination of phylogenetic and expression analysis, I study the role of CYP2J19 as the avian ketolase involved in red ketocarotenoid generation within a clade of well-studied seed-eating passerines, the weaverbirds, and demonstrate a direct association between levels of CYP2J19 expression and red ketocarotenoid-based coloration. Next, I consider the evolution of CYP2J19 across multiple avian lineages. I find evidence for positive selection acting on the gene coding sequence despite its conserved function in colour vision. This finding, though surprising, appears to be common across avian CYP loci in general. Finally, by considering the genomic organisation of CYP2J19 in the zebra finch, I find that the gene underwent a duplication event near the base of the estrildid lineage, which was followed by significant gene conversion post-duplication. Overall, the findings provide strong support for the role of CYP2J19 in red ketocarotenoid pigmentation and demonstrate how an understanding of evolutionary genetics benefit the study of the evolution of adaptive phenotypes.