Many orthopedic conditions in dogs require the placement of bone screws in the proximal tibial metaphysis. Currently, both cortical and cancellous screws are used clinically depending on the surgeon’s preference; however, the ideal screw for use in the proximal tibia has not been determined. Currently, both the manual and power tapping techniques are used during surgical procedures of the proximal tibia in dogs. However, it is unknown if the use of power tapping when placing screws in the canine proximal tibial metaphysis affects screw purchase. Measurement of axial pull-out strength is traditionally used to evaluate and compare the holding power of screws inserted in bone. This study compares the axial pull-out strengths of 3.5 mm cortical and 4.0 mm cancellous screws inserted using manual and power tapping techniques in the proximal tibial metaphysis