Firms‘ resource base is one of the determinants of their capacity to innovate. When firms’ internal base of financial, intangible or technical resources is not sufficient to realize innovation projects, resources provided by other stakeholders can mitigate innovation constraints. This cumulative dissertation intends to shed light on innovation-related collaborations and interactions of three specific kinds of actors. The first article investigates the role innovation plays for investors when screening and evaluating potential investment targets and explains to which extent the investors’ behavior re-orients towards the implementation of innovation-pushing measures once being invested. Also, the second article refers to the interaction between investors and innovative firms: Subsequent to a derivation of an industry-specific business model pattern, the second article analyzes whether and how financing of new and innovative digital health ventures differ between Europe and USA. Adopting a single case study approach, the third article focuses on the interaction between corporate accelerators and innovative firms and identifies shortcomings of Telefonica’s corporate accelerator Wayra.:1 Introduction 2 Theoretical background of dissertation 3 Purpose and focus of dissertation 4 Overview and summaries of dissertation articles 5 First article: The Role of Innovation in Venture Capital and Private Equity Investments in Different Investment Phases 6 Second article: Venture Capital in the Digital Health Industry: Analyzing and Comparing Funding Environment and Business Models of Digital Health Start-ups in USA and Europe 7 Third article: Start-ups in a Corporate Accelerator: What is Satisfying, What is Relevant and What can Corporates Improve? 8 Contribution of dissertation 9 Limitations of dissertation 10 Future Research 11 References