The main idea of this thesis is to de ne and formulate the role of bias estimation in multitarget{multisensor scenarios as a general framework for various measurement types. After a brief introduction of the work that has been done in this thesis, three main contributions are explained in detail, which exercise the novel ideas. Starting with radar measurements, a new bias estimation method that can estimate o set and scaling biases in large network of radars is proposed. Further, Cram er{Rao Lower Bound is calculated for the bias estimation algorithm to show the theoretical accuracy that can be achieved by the proposed method. In practice, communication loss is also part of the distributed systems, which sometimes can not be avoided. A novel technique is also developed to accompany the proposed bias estimation method in this thesis to compensate for communication loss at di erent rates by the use of tracklets. Next, bearing{only measurements are considered. Biases in this type of measurement can be di cult to tackle because the measurement noise and systematic biases are normally larger than in radar measurements. In addition, target observability is sensitive to sensor{target alignment and can vary over time. In a multitarget{ multisensor bearing{only scenario with biases, a new model is proposed for the biases that is decoupled form the bearing{only measurements. These decoupled bias measurements then are used in a maximum likelihood batch estimator to estimate the biases and then be used for compensation. The thesis is then expanded by applying bias estimation algorithms into video sensor measurements. Video sensor measurements are increasingly implemented in distributed systems because of their economical bene ts. However, geo{location and geo{registration of the targets must be considered in such systems. In last part of the thesis, a new approach proposed for modeling and estimation of biases in a two video sensor platform which can be used as a standalone algorithm. The proposed algorithm can estimate the gimbal elevation and azimuth biases e ectively. It is worth noting that in all parts of the thesis, simulation results of various scenarios with di erent parameter settings are presented to support the ideas, the accuracy, mathematical modelings and proposed algorithms. These results show that the bias estimation methods that have been conducted in this thesis are viable and can handle larger biases and measurement errors than previously proposed methods. Finally, the thesis conclude with suggestions for future research in three main directions. / Thesis / Doctor of Philosophy (PhD)