Diss. Nr. 7295 Naturwiss. ETH Zürich.

Würzburg, Univ., Diss., 2009. / Zsfassung in dt. Sprache.

Saarbrücken, Univ., Diss., 1999. / Computerdatei im Fernzugriff.

University, Diss., 2006--Würzburg. / Erscheinungsjahr an der Haupttitelstelle: 2005.

Zugl.: München, Techn. Universiẗat, Diss., 2008.

Bielefeld, University, Diss., 2001. / Dateiformat: tgz, Dateien im PS-Format.

Frankfurt (Main), University, Diss., 2003.

Proefschrift Rijksuniversiteit Groningen. / Met lit.opg. - Met samenvatting in het Nederlands.

This thesis aims to investigate the relationship between increased protein dosage intake and selected haematological and biochemical markers. An experiment was designed using the Wistar laboratory rats of the male gander and similar age (born within +/- 5 days). These specimens were then divides into 3 groups with 10 specimens each. The age of the specimens at the beginning of the experiment was around 62 days. The first group was fed the standard corny mixture ad libitum, while the second group received 6 grams of the standard corny mixture and 10 grams of beef meat per day (thus reflecting the same amount of nitrous compounds as for the first group) and the last (third) group was fed ad libitum with homogenised beef meat. Before the diet was imposed on the three groups, blood samples were collected from all specimen from the lateral tail vein; after the diet was completed, blood samples were collected by in vivo heart puncture. All blood samples were subjected to haematological (using EDTA blood) and biochemical (using blood plasma) analysis. Overall, the following markers were measured: amount of erythrocytes, haematocrit level, haemoglobin level and Mean Corpuscular Volume (MCV) for the haematological analysis and triacylglycerol level, cholesterol level, amount of urea, amount of magnesium and the amount of iron for the biochemical analysis. Dietary induced significant changes were observed for the following markers: number of erythrocytes, levels of haemoglobin and MCV from the haematological analysis and cholesterol levels, amount of magnesium and amount of iron from the biochemical analysis; therefore showing that altered diet can have affect haematological and biochemical blood markers.

The topic of this diploma work was to evaluate the hematological and biochemical indicators of various breeds of dogs. The aim of this work was to evaluate the blood samples taken from 10 dogs and 10 bitches of various breeds and find out the dependency of values in relation to their age, nutrition and sex. The samples were processed and evaluated from May to October 2015. The following was examined from the hematological indicators: RBC, HGB, HCT, MCV, WBC and a blood smear was made, from which a differential count of leucocytes was made. Furthermore, the following biochemical indicators were examined: TP, GLU, CHOL and ATP. The literature research first focused on the basic components of dog feed. Moreover, the hematological and biochemical indicators of blood as well as the methodology of the whole experiment were described. The results were processed with the aid of the RStudio program and the following basic statistical characteristics were counted: median, minimum, maximum and standard deviation. The ANOVA statistical method was used, in which the dependency of values among sex, age category and the type of feed fed to the animals was determined. Furthermore, the values among the breeds were compared. From the differences observed among the breeds, there was an increase in red blood cells in German Shepherds and Dobermans. Dobermans, Labrador Retrievers and German shepherd crossbreeds had increased values of ALT. Significant findings showed that there was an increase in the number of red blood cells and hematocrits in subjects fed with granulated feed as opposed to subjects with a combined diet. The difference was also observed for MCV between the genders. Differences between the genders were found for ALT values. More data would be needed to confirm the relationship to age. ALT values are dependent on the type of feed, where the values are higher in subjects fed with a completely granulated diet. The values of total protein increased in dogs with age. This trend is likely to be observed in bitches. For subjects fed a combined diet (granulated feed + home diet) an increase in the value of total protein was observed with age. For subjects fed granulated feed, this increase was not as significant.